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Granulocyte Colony Stimulating Factor Active Protein

Granulocyte Colony Stimulating Factor, Recombinant, Human (G-CSF)

Purity
Highly Purified
98% by SDS-PAGE. Endotoxin: 0.1 ng/ug
Synonyms
Granulocyte Colony Stimulating Factor; Recombinant; Human (G-CSF); Granulocyte Colony Stimulating Factor active protein
Ordering
For Research Use Only!
Host
Human, recombinant from E Coli
Purity/Purification
Highly Purified
98% by SDS-PAGE. Endotoxin: 0.1 ng/ug
Form/Format
Supplied as a lyophilized powder from 5mM sodium citrate, pH 4.0. Reconstitute in ddH2O and a carrier protein to 0.1-1mg/ml.
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is 0.1ng/ml, corresponding to a specific activity of 1x10e7 units/mg.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O and a carrier protein (0.1% BSA/HSA). Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 3 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Granulocyte Colony Stimulating Factor active protein
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
Product Categories/Family for Granulocyte Colony Stimulating Factor active protein

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
18.7kD
NCBI Official Full Name
granulocyte colony stimulating factor

NCBI Description

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]

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Product Notes

The Granulocyte Colony Stimulating Factor (Catalog #AAA651010) is an Active Protein produced from Human, recombinant from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Granulocyte Colony Stimulating Factor, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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