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Rabbit Vaccinia Virus Polyclonal Antibody | anti-VACV antibody

Vaccinia Virus (Azide Free) (Smallpox, VACV, VV, Lister strain)

Applications
ELISA, Immunocytochemistry, Neutralization Assay
Purity
Purified IgG fraction to a purity of >=95%.
Synonyms
Vaccinia Virus; Polyclonal Antibody; Vaccinia Virus (Azide Free) (Smallpox; VACV; VV; Lister strain); anti-VACV antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes Vaccinia, purified virions. Recognizes the B5R and the A33R proteins. Species Crossreactivity: Lister, New York City, MVA strains of Vaccinia and Monkeypox. Does not crossreact with Parainfluenza (1-3), RSV, Adeno, Influenza A & B, HSV (1) or uninfected cells.
Purity/Purification
Purified IgG fraction to a purity of >=95%.
Form/Format
Supplied as a liquid in PBS, pH 7.4. No stabilizing proteins added. No preservative added. Also available with azide.
Concentration
~4-5mg/ml (varies by lot)
Applicable Applications for anti-VACV antibody
ELISA (EIA), Fluorescence Microscopy, Immunocytochemistry(ICC), Plaque-Reduction Neutralization Test (PRNT)
Application Notes
This iteme also Conjugation purposes.
Immunogen
New York City Board of Health strain (NYCBOH).
Note
Preservative Free
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-VACV antibody
Vaccinia virus (VACV or VV) is a large, complex enveloped virus belonging to the poxvirus family of viruses. It has a linear double-stranded DNA genome, which is approximately 190kb in length and encodes for approximately 250 genes. The dimensions of the virion are roughly 360 × 270 × 250nm. Vaccinia virus is well-known for its role as a vaccine that eradicated the smallpox disease from our world, making it the first human disease to be successfully eradicated by mankind. This endeavor was carried out by the World Health Organization under the Smallpox Eradication Program. Post eradication of smallpox, scientists have been studying vaccinia virus to use as a tool for delivering genes into biological tissues (gene therapy and genetic engineering). Moreover, due to recent concerns about smallpox resurfacing as a possible agent for bioterrorism, scientists have renewed their interests in studying vaccinia virus.
Product Categories/Family for anti-VACV antibody
References
1. Holgado MP, et al. Deletion of A44L, A46R and C12L Vaccinia Virus Genes from the MVA Genome Improved the Vector Immunogenicity by Modifying the Innate Immune Response Generating Enhanced and Optimized Specific T-Cell Responses. Viruses 2016, 8(5), 139; doi:10.3390/v8050139.

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Product Notes

The VACV (Catalog #AAA6505420) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Vaccinia Virus can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Fluorescence Microscopy, Immunocytochemistry(ICC), Plaque-Reduction Neutralization Test (PRNT). This iteme also Conjugation purposes. Researchers should empirically determine the suitability of the VACV for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vaccinia Virus, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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