Interleukin 4 Active Protein | il4 active protein
Interleukin 4, Recombinant, Mouse (IL-4, B Cell Stimulatory Factor 1, BSF1, Binetrakin, HCGF, Hodgkin's Cell Growth Factor, IA Inducing Factor, Lymphocyte Stimulatory Factor 1, Macrophage Fusion Factor, Mast Cell Growth Factor 2, MCGF2, MFF, MGC79402, Pit
Gene Names
il4; bsf1; il-4; bcgf1; bcgf-1
Purity
Highly Purified98% by SDS-PAGE analyses.
Synonyms
Interleukin 4; Recombinant; Mouse (IL-4; B Cell Stimulatory Factor 1; BSF1; Binetrakin; HCGF; Hodgkin's Cell Growth Factor; IA Inducing Factor; Lymphocyte Stimulatory Factor 1; Macrophage Fusion Factor; Mast Cell Growth Factor 2; MCGF2; MFF; MGC79402; Pit; il4 active protein
Purity/Purification
Highly Purified
98% by SDS-PAGE analyses.
98% by SDS-PAGE analyses.
Form/Format
Supplied as a lophilized protein without additives.
Sequence
MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
Biological Activity
Fully biologically active when compared to standards. The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Endotoxin Level
0.1ng/ug (1EU/ug).
Reconstitution
Reconstitute in water to a concentration of 1mg/ml. This solution can then be diluted into other aqueous buffers.
Preparation and Storage
Lyophilized powder is stable for at least 12 months at -20 degree C Reconstituted product must be stored in working aliquots at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for il4 active protein
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5kD globular protein containing 120 amino acid residues.
Product Categories/Family for il4 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13.5kD
NCBI Official Full Name
interleukin 4
NCBI Official Synonym Full Names
interleukin 4
NCBI Official Symbol
il4
NCBI Official Synonym Symbols
bsf1; il-4; bcgf1; bcgf-1
NCBI Protein Information
interleukin 4; interleukin-4
Protein Family
Similar Products
Product Notes
The il4 (Catalog #AAA650491) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S. It is sometimes possible for the material contained within the vial of "Interleukin 4, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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