Goat anti-Human CADM4 Polyclonal Antibody | anti-CADM4 antibody

CADM4, CT (Cell Adhesion Molecule 4, Immunoglobulin Superfamily Member 4C, IgSF4C, Nectin-like Protein 4, NECL-4, TSLC1-like Protein 2, IGSF4C, NECL4, TSLL2)

Cat. Num. AAA649832

• Gene Names: CADM4; NECL4; TSLL2; IGSF4C; Necl-4; synCAM4
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: CADM4; Polyclonal Antibody; CT (Cell Adhesion Molecule 4; Immunoglobulin Superfamily Member 4C; IgSF4C; Nectin-like Protein 4; NECL-4; TSLC1-like Protein 2; IGSF4C; NECL4; TSLL2); Anti -CADM4; anti-CADM4 antibody

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human CADM4. Species sequence homology: Canine, mouse, rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

• Applicable Applications for anti-CADM4 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: ELISA: 1:32,000; Western Blot: 0.03-0.1ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml
• Immunogen: Synthetic peptide corresponding to C-REAFLNGSDGHKRKE from C-terminus of human IGSF4C.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))

Testing Data

(Staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). B) (0.05ug/ml) Primary incubation was 1 hour. Detected by chemiluminescence.)

Related Product Information for anti-CADM4 antibody

IGSF4C involved in the cell-cell adhesion. This protein has calcium- and magnesium-independent cell-cell adhesion activity. The protein may have tumor-suppressor activity.

Product Categories/Family for anti-CADM4 antibody

Antibodies; Abs to Tumor Suppressors

NCBI and Uniprot Product Information

• NCBI GI #: 21686977
• NCBI GeneID: 199731
• NCBI Accession #: NP_660339.1
• NCBI GenBank Nucleotide #: NM_145296.1
• UniProt Accession #: Q8NFZ8; Q9Y4A4; B2R7L5
• Molecular Weight: 42,785 Da
• NCBI Official Full Name: cell adhesion molecule 4
• NCBI Official Synonym Full Names: cell adhesion molecule 4
• NCBI Official Symbol: CADM4
• NCBI Official Synonym Symbols: NECL4; TSLL2; IGSF4C; Necl-4; synCAM4
• NCBI Protein Information: cell adhesion molecule 4; TSLC1-like 2; nectin-like 4; TSLC1-like protein 2; nectin-like protein 4; immunoglobulin superfamily member 4C; immunoglobulin superfamily, member 4C
• UniProt Protein Name: Cell adhesion molecule 4
• Protein Family: Cell adhesion molecule
• UniProt Gene Name: CADM4
• UniProt Synonym Gene Names: IGSF4C; NECL4; TSLL2; IgSF4C; NECL-4
• UniProt Entry Name: CADM4_HUMAN

Uniprot Description

Function: Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity. Ref.4

Subunit structure: Monomer and homodimer. Ref.4

Subcellular location: Membrane; Single-pass type I membrane protein

Potential.

Tissue specificity: Expressed in brain, prostate, brain, kidney and some other organs. Ref.1 Ref.4

Post-translational modification: N-glycosylated

By similarity.

Sequence similarities: Belongs to the nectin family.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Sequence caution: The sequence AAC32740.1 differs from that shown. Reason: Erroneous gene model prediction.