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Western Blot (WB) (Western blot analysis of PEX11A Antibody (N-term) in MDA-MB468 cell line lysates (35ug/lane). PEX11A (arrow) was detected using the purified Pab.)

Rabbit anti-Human Peroxisomal Biogenesis Factor 11 alpha Polyclonal Antibody | anti-PEX11A antibody

Peroxisomal Biogenesis Factor 11 alpha, NT (Peroxisomal Biogenesis Factor 11A, Peroxisomal Membrane Protein 11A, Peroxin-11A, PEX11-alpha, PEX11A, PEX11, Protein PEX11 Homolog alpha, 28kD Peroxisomal Integral Membrane Protein, PMP28, HsPEX11p, MGC119947,

Gene Names
PEX11A; PMP28; hsPEX11p; PEX11-ALPHA
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Immunoaffinity chromatography.
Synonyms
Peroxisomal Biogenesis Factor 11 alpha; Polyclonal Antibody; NT (Peroxisomal Biogenesis Factor 11A; Peroxisomal Membrane Protein 11A; Peroxin-11A; PEX11-alpha; PEX11A; PEX11; Protein PEX11 Homolog alpha; 28kD Peroxisomal Integral Membrane Protein; PMP28; HsPEX11p; MGC119947; ; anti-PEX11A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PEX11A.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-PEX11A antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-1:500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the N-terminal region of human PEX11A (KLH).
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of PEX11A Antibody (N-term) in MDA-MB468 cell line lysates (35ug/lane). PEX11A (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of PEX11A Antibody (N-term) in MDA-MB468 cell line lysates (35ug/lane). PEX11A (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with PEX11A Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with PEX11A Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(PEX11A Antibody (N-term) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (PEX11A Antibody (N-term) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-PEX11A antibody
References
1. Sacksteder, K.A., et.al., J. Cell Biol. 148(5), 931-944 (2000). 2. Shimizu, M., et.al., J. Biochem. 139(3), 563-573 (2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,353 Da
NCBI Official Full Name
peroxisomal membrane protein 11A isoform 1
NCBI Official Synonym Full Names
peroxisomal biogenesis factor 11 alpha
NCBI Official Symbol
PEX11A
NCBI Official Synonym Symbols
PMP28; hsPEX11p; PEX11-ALPHA
NCBI Protein Information
peroxisomal membrane protein 11A; peroxin-11A; protein PEX11 homolog alpha; peroxisomal biogenesis factor 11A; 28 kDa peroxisomal integral membrane protein
UniProt Protein Name
Peroxisomal membrane protein 11A
UniProt Gene Name
PEX11A
UniProt Synonym Gene Names
PEX11; HsPEX11p; PMP28; PEX11-alpha
UniProt Entry Name
PX11A_HUMAN

NCBI Description

This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

Uniprot Description

PEX11A: May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane. Belongs to the peroxin-11 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q26.1

Cellular Component: peroxisomal membrane; integral to peroxisomal membrane; protein complex; peroxisome

Molecular Function: protein binding; protein homodimerization activity

Biological Process: peroxisome fission; peroxisome organization and biogenesis; brown fat cell differentiation; cellular lipid metabolic process; signal transduction; peroxisome membrane biogenesis

Research Articles on PEX11A

Similar Products

Product Notes

The PEX11A pex11a (Catalog #AAA6492748) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Peroxisomal Biogenesis Factor 11 alpha, NT (Peroxisomal Biogenesis Factor 11A, Peroxisomal Membrane Protein 11A, Peroxin-11A, PEX11-alpha, PEX11A, PEX11, Protein PEX11 Homolog alpha, 28kD Peroxisomal Integral Membrane Protein, PMP28, HsPEX11p, MGC119947, reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Peroxisomal Biogenesis Factor 11 alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-1:500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PEX11A pex11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peroxisomal Biogenesis Factor 11 alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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