Western Blot (WB)
(Western Blot analysis of PDZD3 expression in transfected 293T cell line by PDZD3 polyclonal antibody. Lane 1: PDZD3 transfected lysate (52.5kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human PDZD3 Polyclonal Antibody | anti-PDZD3 antibody
PDZD3 (IKEPP, NHERF4, PDZK2, Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF4, Intestinal and Kidney-enriched PDZ Protein, Natrium-phosphate Cotransporter Iia C-terminal-associated Protein 2, PDZ Domain-containing Protein 2, PDZ Domain-containing Protein 3
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
PDZD3; Polyclonal Antibody; PDZD3 (IKEPP; NHERF4; PDZK2; Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF4; Intestinal and Kidney-enriched PDZ Protein; Natrium-phosphate Cotransporter Iia C-terminal-associated Protein 2; PDZ Domain-containing Protein 2; PDZ Domain-containing Protein 3; Anti -PDZD3 (IKEPP; anti-PDZD3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PDZD3.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MEKAADLQDTASLTLKFKFNPKLGIDNPVLSLAEDHDPYDPWSLERPRFCLLSKEEGKSFGFHLQQELGRAGHVVCRVDPGTSAQRQGLQEGDRILAVNNDVVEHEDYAVVVRRIRASSPRVLLTVLARHAHDVARAQLGEDAHLCPTLGPGVRPRLCHIVKDEGGFGFSVTHGNQGPFWLVLSTGGAAERAGVPPGARLLEVNGLWQSGQQVTLLVAGPEVEEQCRQLGLPLAAPLAEGWALPTKPRCLHLEKGPQGFGFLLREEKGLDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGESVEGLGHEETVSRIQGQGSCVSLTVVDPEADRFFSMVRLSPLLFLENTEAPASPQGSSSASLVETEDPSLEDTSVPSVPLGSRQCFLYPGPGGSYGFRLSCVASGPRLFISQVTPGGSAARAGLQVGDVILEVNGYPVGGQNDLERLQQLPEAEPPLCLKLAARSLRGLEAWIPPGAAEDWALASDLL
Applicable Applications for anti-PDZD3 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human PDZD3, aa1-491 (NP_079067.2).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of PDZD3 expression in transfected 293T cell line by PDZD3 polyclonal antibody. Lane 1: PDZD3 transfected lysate (52.5kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PDZD3 expression in transfected 293T cell line by PDZD3 polyclonal antibody. Lane 1: PDZD3 transfected lysate (52.5kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-PDZD3 antibody
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).
Product Categories/Family for anti-PDZD3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Na(+)/H(+) exchange regulatory cofactor NHE-RF4
NCBI Official Symbol
PDZD3
NCBI Protein Information
PDZ domain containing 3
Protein Family
Similar Products
Product Notes
The PDZD3 (Catalog #AAA648839) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDZD3 (IKEPP, NHERF4, PDZK2, Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF4, Intestinal and Kidney-enriched PDZ Protein, Natrium-phosphate Cotransporter Iia C-terminal-associated Protein 2, PDZ Domain-containing Protein 2, PDZ Domain-containing Protein 3 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDZD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the PDZD3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MEKAADLQDT ASLTLKFKFN PKLGIDNPVL SLAEDHDPYD PWSLERPRFC LLSKEEGKSF GFHLQQELGR AGHVVCRVDP GTSAQRQGLQ EGDRILAVNN DVVEHEDYAV VVRRIRASSP RVLLTVLARH AHDVARAQLG EDAHLCPTLG PGVRPRLCHI VKDEGGFGFS VTHGNQGPFW LVLSTGGAAE RAGVPPGARL LEVNGLWQSG QQVTLLVAGP EVEEQCRQLG LPLAAPLAEG WALPTKPRCL HLEKGPQGFG FLLREEKGLD GRPGQFLWEV DPGLPAKKAG MQAGDRLVAV AGESVEGLGH EETVSRIQGQ GSCVSLTVVD PEADRFFSMV RLSPLLFLEN TEAPASPQGS SSASLVETED PSLEDTSVPS VPLGSRQCFL YPGPGGSYGF RLSCVASGPR LFISQVTPGG SAARAGLQVG DVILEVNGYP VGGQNDLERL QQLPEAEPPL CLKLAARSLR GLEAWIPPGA AEDWALASDL L. It is sometimes possible for the material contained within the vial of "PDZD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
