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Western Blot (WB) (The anti-EPS15R Pab is used in Western blot to detect EPS15R in Y79 cell lysate.)

Rabbit anti-Human EPS15R Polyclonal Antibody | anti-EPS15R antibody

EPS15R, NT (Epidermal Growth Factor Receptor Substrate 15-like 1, Eps15-related Protein, EPS15L1) (APC)

Gene Names
EPS15L1; EPS15R
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein G Affinity Chromatography.
Synonyms
EPS15R; Polyclonal Antibody; NT (Epidermal Growth Factor Receptor Substrate 15-like 1; Eps15-related Protein; EPS15L1) (APC); anti-EPS15R antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human EPS15R.
Purity/Purification
Purified by Protein G Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-EPS15R antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the N-terminal region of human EPS15R (KLH).
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(The anti-EPS15R Pab is used in Western blot to detect EPS15R in Y79 cell lysate.)

Western Blot (WB) (The anti-EPS15R Pab is used in Western blot to detect EPS15R in Y79 cell lysate.)
Product Categories/Family for anti-EPS15R antibody
References
1. J Biol Chem. 2002 Aug 23;277(34):30746-53. 2. J Biol Chem. 2002 Mar 15;277(11):8941-8. 3. J Biol Chem. 1998 Jan 30;273(5):3003-12. 4. Cancer Res. 1997 Dec 15;57(24):5498-504. 5. J Biol Chem. 1995 Jun 23;270(25):15341-7.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
95kDa
NCBI Official Full Name
epidermal growth factor receptor substrate 15-like 1 isoform 2
NCBI Official Synonym Full Names
epidermal growth factor receptor pathway substrate 15 like 1
NCBI Official Symbol
EPS15L1
NCBI Official Synonym Symbols
EPS15R
NCBI Protein Information
epidermal growth factor receptor substrate 15-like 1
UniProt Protein Name
Epidermal growth factor receptor substrate 15-like 1
UniProt Gene Name
EPS15L1
UniProt Synonym Gene Names
EPS15R; Eps15R
UniProt Entry Name
EP15R_HUMAN

Uniprot Description

EPS15R: epidermal growth factor receptor substrate protein 15R. Contains three EH domains which are implicated in endocytosis, vesicle transport and signal transduction. All three EH domains contain calcium-binding domains ofthe EF-hand type. Contains 2 UIM motifs, which are is responsible for ubiquitin recognition and monoubiquitination. May function as an adaptor between ubiquitinated proteins and the clathrin coat or other endocytic scaffolds.

Protein type: Adaptor/scaffold; Vesicle

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: membrane; plasma membrane; coated pit; nucleus

Molecular Function: protein binding; calcium ion binding

Biological Process: negative regulation of epidermal growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway; endocytosis

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Product Notes

The EPS15R eps15l1 (Catalog #AAA6474620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPS15R, NT (Epidermal Growth Factor Receptor Substrate 15-like 1, Eps15-related Protein, EPS15L1) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EPS15R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-1:500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the EPS15R eps15l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPS15R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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