Rabbit anti-Human TMF1 Polyclonal Antibody | anti-TMF1 antibody

TMF1 (TATA Element Modulatory Factor, TMF, Androgen Receptor Coactivator 160kD Protein, Androgen Receptor-Associated Protein of 160kD, TMF1, ARA160) (MaxLight 750)

Cat. Num. AAA6459801

• Gene Names: TMF1; TMF; ARA160
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TMF1; Polyclonal Antibody; TMF1 (TATA Element Modulatory Factor; TMF; Androgen Receptor Coactivator 160kD Protein; Androgen Receptor-Associated Protein of 160kD; ARA160) (MaxLight 750); anti-TMF1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TMF1. Species Crossreactivity: human
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

• Applicable Applications for anti-TMF1 antibody: Western Blot (WB)
• Application Notes: WB: 1:1000; Applications are based on unconjugated antibody.
• Immunogen: KLH conjugated synthetic peptide corresponding to aa447-480 at the Central region of human TMF1.
• Conjugate: MaxLight750
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Categories/Family for anti-TMF1 antibody

Antibodies; Receptors

References

Garcia J.A., et al. Proc. Natl. Acad. Sci. U.S.A. 89:9372-9376(1992). Hsiao P.W., et al. J. Biol. Chem. 274:22373-22379(1999). Totoki Y., et al. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Muzny D.M., et al. Nature 440:1194-1198(2006). Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

• NCBI GI #: 218511858
• NCBI GeneID: 7110
• UniProt Accession #: P82094; Q17R87; Q59GK0; B7ZLJ2
• Molecular Weight: 1093
• NCBI Official Full Name: TATA element modulatory factor
• NCBI Official Synonym Full Names: TATA element modulatory factor 1
• NCBI Official Symbol: TMF1
• NCBI Official Synonym Symbols: TMF; ARA160
• NCBI Protein Information: TATA element modulatory factor; androgen receptor coactivator 160 kDa protein; androgen receptor-associated protein of 160 kDa
• UniProt Protein Name: TATA element modulatory factor
• Protein Family: TATA element modulatory factor
• UniProt Gene Name: TMF1
• UniProt Synonym Gene Names: ARA160; TMF
• UniProt Entry Name: TMF1_HUMAN

Uniprot Description

TMF1: Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 3p14.1

Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum; nucleus

Molecular Function: protein binding; DNA binding; transcription cofactor activity

Biological Process: acrosome formation; transcription from RNA polymerase II promoter; positive regulation of cytokine production; luteinizing hormone secretion; sperm motility; Leydig cell differentiation; regulation of transcription, DNA-dependent; defense response to bacterium; spermatid nuclear differentiation; negative regulation of apoptosis