Rabbit Srf Polyclonal Antibody | anti-Srf antibody

Srf (Serum Response Factor, SRF, Srf) (APC)

Cat. Num. AAA6459496

• Gene Names: Srf; AW049942; AW240594
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: Srf; Polyclonal Antibody; Srf (Serum Response Factor; SRF; Srf) (APC); anti-Srf antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes Srf. Species Crossreactivity: mouse, rat
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-Srf antibody: Western Blot (WB)
• Application Notes: WB: 1:1000; Applications are based on unconjugated antibody.
• Immunogen: KLH conjugated synthetic peptide corresponding to aa489-524 at the C-terminal region of human (Mouse) Srf.
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Categories/Family for anti-Srf antibody

Antibodies; Transcription Factors

References

Miwa T., et al. Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases. Zhang X., et al. J. Biol. Chem. 279:55626-55632(2004). Parlakian A., et al. Mol. Cell. Biol. 24:5281-5289(2004). Zhang X., et al. Biochem. Biophys. Res. Commun. 346:794-801(2006). Villen J., et al. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).

NCBI and Uniprot Product Information

• NCBI GI #: 10048414
• NCBI GeneID: 20807
• NCBI Accession #: NP_065239.1
• NCBI GenBank Nucleotide #: NM_020493.2
• UniProt Accession #: Q9JM73
• Molecular Weight: 51,247 Da
• NCBI Official Full Name: serum response factor
• NCBI Official Synonym Full Names: serum response factor
• NCBI Official Symbol: Srf
• NCBI Official Synonym Symbols: AW049942; AW240594
• NCBI Protein Information: serum response factor
• UniProt Protein Name: Serum response factor
• Protein Family: Serum response factor
• UniProt Gene Name: Srf
• UniProt Synonym Gene Names: SRF
• UniProt Entry Name: SRF_MOUSE

Uniprot Description

SRF: a transcription factor of the MADS domain family that binds to the serum response element (SRE). Regulates the transcription of immediate early genes including c-fos. Binds DNA as a multimer, probably a dimer.

Protein type: Transcription factor; Motility/polarity/chemotaxis

Cellular Component: cell; cytoplasm; nuclear chromatin; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein dimerization activity; protein binding; protein homodimerization activity; DNA binding; chromatin DNA binding; sequence-specific DNA binding; histone deacetylase binding; chromatin binding; transcription factor binding; transcription factor activity

Biological Process: developmental growth; positive regulation of transcription, DNA-dependent; positive regulation of axon extension; heart development; multicellular organismal development; gastrulation; muscle maintenance; cell-cell adhesion; tangential migration from the subventricular zone to the olfactory bulb; morphogenesis of an epithelial sheet; neurite development; platelet activation; skin morphogenesis; transcription, DNA-dependent; leukocyte differentiation; actin filament organization; trophectodermal cell differentiation; patterning of blood vessels; regulation of water loss via skin; cell migration during sprouting angiogenesis; mesoderm formation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of cell differentiation; actin cytoskeleton organization and biogenesis; transcription from RNA polymerase II promoter; erythrocyte development; positive regulation of transcription by glucose; cell-matrix adhesion; response to hormone stimulus; neuron migration; cardiac myofibril assembly; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; positive regulation of smooth muscle contraction; heart looping; negative regulation of cell migration; associative learning; positive thymic T cell selection; regulation of cell adhesion; positive regulation of filopodium formation; in utero embryonic development; hippocampus development; sarcomere organization; mRNA transcription from RNA polymerase II promoter; contractile actin filament bundle formation; long-term memory; response to cytokine stimulus; stress fiber formation; platelet formation