Rabbit PPP3R1 Polyclonal Antibody | anti-PPP3R1 antibody

PPP3R1 (Protein phosphatase 3 Regulatory Subunit 1, ALNB1, CNB, CNB1) (HRP)

Cat. Num. AAA6432726

• Gene Names: PPP3R1; CNB; CNB1; CALNB1
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, Immunoprecipitation
• Purity: Purified by affinity chromatography.
• Synonyms: PPP3R1; Polyclonal Antibody; PPP3R1 (Protein phosphatase 3 Regulatory Subunit 1; ALNB1; CNB; CNB1) (HRP); anti-PPP3R1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes PPP3R1. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-PPP3R1 antibody: Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: IHC: 1:50-1:200; WB: 1:500-1:2000; IP: 1:20-1:50; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human PPP3R1.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of K-562 cells lines, using PPP3R1 antibody.)

Product Categories/Family for anti-PPP3R1 antibody

Antibodies; Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 52000904
• NCBI GeneID: 5534
• UniProt Accession #: P63098; P06705; P15117; Q08044; Q53SL0; B2RC10; B5MDU4
• Molecular Weight: 170
• NCBI Official Full Name: Calcineurin subunit B type 1
• NCBI Official Synonym Full Names: protein phosphatase 3, regulatory subunit B, alpha
• NCBI Official Symbol: PPP3R1
• NCBI Official Synonym Symbols: CNB; CNB1; CALNB1
• NCBI Protein Information: calcineurin subunit B type 1; calcineurin B, type I (19kDa); protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 (f
• UniProt Protein Name: Calcineurin subunit B type 1
• UniProt Gene Name: PPP3R1
• UniProt Synonym Gene Names: CNA2; CNB
• UniProt Entry Name: CANB1_HUMAN

Uniprot Description

PPP3R1: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. Belongs to the calcineurin regulatory subunit family.

Protein type: Protein phosphatase, regulatory subunit; Cell development/differentiation; Apoptosis; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p15

Cellular Component: nucleoplasm; cytosol; calcineurin complex; sarcolemma

Molecular Function: calmodulin binding; protein domain specific binding; protein binding; calcium-dependent protein serine/threonine phosphatase activity; calcium ion binding

Biological Process: calcineurin-NFAT signaling pathway; positive regulation of NFAT protein import into nucleus; dephosphorylation; apoptosis; innate immune response; positive regulation of transcription from RNA polymerase II promoter