Rabbit PIK3R3 Polyclonal Antibody | anti-PIK3R3 antibody
PIK3R3 (Phosphoinositide-3-kinase, Regulatory Subunit 3 (gamma), p55, p55-GAMMA) (AP)
Gene Names
PIK3R3; p55; p55PIK; p55-GAMMA
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Western Blot
Purity
Purified by affinity chromatography.
Synonyms
PIK3R3; Polyclonal Antibody; PIK3R3 (Phosphoinositide-3-kinase; Regulatory Subunit 3 (gamma); p55; p55-GAMMA) (AP); anti-PIK3R3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes PIK3R3. Species Crossreactivity: human, mouse, rat
Purity/Purification
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-PIK3R3 antibody
Immunoprecipitation (IP), Western Blot (WB)
Application Notes
IP: 1:20-1:50
WB: 1:500-1:2000
Applications are based on unconjugated antibody.
WB: 1:500-1:2000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide corresponding to human PIK3R3.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Product Categories/Family for anti-PIK3R3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
461
NCBI Official Full Name
Phosphatidylinositol 3-kinase regulatory subunit gamma
NCBI Official Synonym Full Names
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
NCBI Official Symbol
PIK3R3
NCBI Official Synonym Symbols
p55; p55PIK; p55-GAMMA
NCBI Protein Information
phosphatidylinositol 3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; PI3K regulatory subunit gamma; PI3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p55-gamma; phosphatidylinositol 3-kinase 55 kDa regulatory subunit
UniProt Protein Name
Phosphatidylinositol 3-kinase regulatory subunit gamma
Protein Family
UniProt Gene Name
PIK3R3
UniProt Synonym Gene Names
PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma
UniProt Entry Name
P55G_HUMAN
Uniprot Description
PIK3R3: Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Heterodimer of a regulatory subunit PIK3R3 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts with AXL. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. Belongs to the PI3K p85 subunit family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Kinase, lipid
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: cytosol; phosphoinositide 3-kinase complex
Molecular Function: protein binding; 1-phosphatidylinositol-3-kinase activity; phosphoinositide 3-kinase regulator activity
Biological Process: phospholipid metabolic process; phosphatidylinositol biosynthetic process; insulin receptor signaling pathway; regulation of phosphoinositide 3-kinase activity
Research Articles on PIK3R3
Similar Products
Product Notes
The PIK3R3 pik3r3 (Catalog #AAA6431655) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIK3R3 (Phosphoinositide-3-kinase, Regulatory Subunit 3 (gamma), p55, p55-GAMMA) (AP) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PIK3R3 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Western Blot (WB). IP: 1:20-1:50 WB: 1:500-1:2000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PIK3R3 pik3r3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIK3R3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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