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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using LETMD1 antibody.)

Rabbit LETMD1 Polyclonal Antibody | anti-LETMD1 antibody

LETMD1 (LETM1 Domain-containing Protein 1, HCCR1, HCCR-1, HCCR-2, HCRR-2, 1110019O13Rik) (FITC)

Gene Names
LETMD1; HCCR1; HCCR-1; HCCR-2; HCRR-2; 1110019O13Rik
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, Immunohistochemistry
Purity
Purified by affinity chromatography.
Synonyms
LETMD1; Polyclonal Antibody; LETMD1 (LETM1 Domain-containing Protein 1; HCCR1; HCCR-1; HCCR-2; HCRR-2; 1110019O13Rik) (FITC); anti-LETMD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes LETMD1. Species Crossreactivity: human, mouse, rat
Purity/Purification
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-LETMD1 antibody
Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
IF: 1:50-1:200
WB: 1:500-1:2000
IHC: 1:50-1:200
Applications are based on unconjugated antibody.
Immunogen
Recombinant protein corresponding to human LETMD1.
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using LETMD1 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using LETMD1 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of MCF7 cell using LETMD1 antibody. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of MCF7 cell using LETMD1 antibody. Blue: DAPI for nuclear staining.)
Product Categories/Family for anti-LETMD1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
360
NCBI Official Full Name
LETM1 domain-containing protein 1
NCBI Official Synonym Full Names
LETM1 domain containing 1
NCBI Official Symbol
LETMD1
NCBI Official Synonym Symbols
HCCR1; HCCR-1; HCCR-2; HCRR-2; 1110019O13Rik
NCBI Protein Information
LETM1 domain-containing protein 1; regulator of TP53; cervical cancer proto-oncogene 2 protein; cervical cancer 1 proto-oncogene protein p40
UniProt Protein Name
LETM1 domain-containing protein 1
UniProt Gene Name
LETMD1
UniProt Entry Name
LTMD1_HUMAN

NCBI Description

This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011]

Uniprot Description

LETMD1: Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Oncoprotein; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: mitochondrial outer membrane; integral to membrane

Molecular Function: protein binding

Research Articles on LETMD1

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Product Notes

The LETMD1 letmd1 (Catalog #AAA6424629) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LETMD1 (LETM1 Domain-containing Protein 1, HCCR1, HCCR-1, HCCR-2, HCRR-2, 1110019O13Rik) (FITC) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LETMD1 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC). IF: 1:50-1:200 WB: 1:500-1:2000 IHC: 1:50-1:200 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LETMD1 letmd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LETMD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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