Rabbit anti-Human Atrial Natriuretic Peptide, beta Polyclonal Antibody | anti-NPR2 antibody

Atrial Natriuretic Peptide, beta (ANP, Atrial Natriuretic Factor, ANF, ATFB6, CDD-ANF, Natriuretic Peptide A, NPPA, Prepronatriodilatin, PND)

Cat. Num. AAA641235

• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Serum; Serum
• Synonyms: Atrial Natriuretic Peptide; beta; Polyclonal Antibody; beta (ANP; Atrial Natriuretic Factor; ANF; ATFB6; CDD-ANF; Natriuretic Peptide A; NPPA; Prepronatriodilatin; PND); Anti -Atrial Natriuretic Peptide; anti-NPR2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human beta-ANP.
• Purity/Purification: Serum; Serum
• Form/Format: Supplied as a lyophilized powder. Reconstitute with sterile dH2O.

• Applicable Applications for anti-NPR2 antibody: Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Immunohistochemistry and Immunofluorescence.; Dilution: Immunofluorescence: 1:200; Immunohistochemistry (PAP or ABC): 1:500
• Immunogen: Synthetic peptide corresponding to human beta-ANP.
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for anti-NPR2 antibody

Antibodies; Abs to Cardiac Markers

NCBI and Uniprot Product Information

• NCBI GI #: 27806517
• NCBI GeneID: 281357
• NCBI Accession #: NP_776551.1
• NCBI GenBank Nucleotide #: NM_174126.2
• UniProt Accession #: P46197
• Molecular Weight: 117,146 Da
• NCBI Official Full Name: atrial natriuretic peptide receptor 2
• NCBI Official Synonym Full Names: natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
• NCBI Official Symbol: NPR2
• NCBI Protein Information: atrial natriuretic peptide receptor 2; GC-B; ANP-B; ANPRB; NPR-B; ANPR-B; guanylate cyclase B; atrionatriuretic peptide receptor B; atrial natriuretic peptide receptor B; atrial natriuretic peptide B-type receptor; atrial natriuretic peptide receptor type B
• UniProt Protein Name: Atrial natriuretic peptide receptor 2
• Protein Family: Atrial natriuretic peptide receptor
• UniProt Gene Name: NPR2
• UniProt Synonym Gene Names: ANP-B; ANPR-B; NPR-B; GC-B
• UniProt Entry Name: ANPRB_BOVIN

Uniprot Description

Function: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth

By similarity.

Catalytic activity: GTP = 3',5'-cyclic GMP + diphosphate.

Subcellular location: Membrane; Single-pass type I membrane protein.

Post-translational modification: Phosphorylation of the protein kinase-like domain is required for full activation by CNP

By similarity.

Sequence similarities: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.Contains 1 guanylate cyclase domain.Contains 1 protein kinase domain.