Rabbit ATP6V1G3 Polyclonal Antibody | anti-ATP6V1G3 antibody

ATP6V1G3 (V-type Proton ATPase Subunit G 3, V-ATPase Subunit G 3, Vma10, ATP6G3) (AP)

Cat. Num. AAA6407829

• Gene Names: ATP6V1G3; Vma10; ATP6G3
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: ATP6V1G3; Polyclonal Antibody; ATP6V1G3 (V-type Proton ATPase Subunit G 3; V-ATPase Subunit G 3; Vma10; ATP6G3) (AP); anti-ATP6V1G3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes ATP6V1G3. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-ATP6V1G3 antibody: Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: IHC: 1:50-1:200; WB: 1:200-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide corresponding to human ATP6V1G3.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Categories/Family for anti-ATP6V1G3 antibody

Antibodies; Enzymes; ATPase

NCBI and Uniprot Product Information

• NCBI GI #: 72533514
• NCBI GeneID: 127124
• UniProt Accession #: Q96LB4; Q495K2; Q495K4; Q5T9L6
• Molecular Weight: 13,917 Da
• NCBI Official Full Name: ATP6V1G3 protein
• NCBI Official Synonym Full Names: ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
• NCBI Official Symbol: ATP6V1G3
• NCBI Official Synonym Symbols: Vma10; ATP6G3
• NCBI Protein Information: V-type proton ATPase subunit G 3; V-ATPase G3 subunit; V-ATPase G subunit 3; V-ATPase subunit G 3; V-ATPase 13 kDa subunit 3; vacuolar proton pump G subunit 3; vacuolar proton pump subunit G 3; vacuolar proton pump, subunit G3; vacuolar ATP synthase subun
• UniProt Protein Name: V-type proton ATPase subunit G 3
• Protein Family: V-type proton ATPase
• UniProt Gene Name: ATP6V1G3
• UniProt Synonym Gene Names: ATP6G3; V-ATPase subunit G 3
• UniProt Entry Name: VATG3_HUMAN

NCBI Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subunit structure: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d)

By similarity.

Tissue specificity: Kidney. Ref.1

Sequence similarities: Belongs to the V-ATPase G subunit family.