Rabbit anti-Human TBL2 Polyclonal Antibody | anti-TBL2 antibody

TBL2 (WBSCR13, Transducin beta-like Protein 2, WS beta-transducin Repeats Protein, Williams-Beuren Syndrome Chromosomal Region 13 Protein, UNQ563/PRO1125, DKFZp434N024, DKFZP43N024, MGC134739) APC

Cat. Num. AAA6396116

• Gene Names: TBL2; WBSCR13; WS-betaTRP
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TBL2; Polyclonal Antibody; TBL2 (WBSCR13; Transducin beta-like Protein 2; WS beta-transducin Repeats Protein; Williams-Beuren Syndrome Chromosomal Region 13 Protein; UNQ563/PRO1125; DKFZp434N024; DKFZP43N024; MGC134739) APC; anti-TBL2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TBL2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-TBL2 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human TBL2, aa1-447 (NP_036585.1).
• Immunogen Sequence: MELSQMSELMGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKANGFPPDKSSGSKKQKQYQRIRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTRRGEKEECFERVHGECIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQAQETLKSLGALKK
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(TBL2 rabbit polyclonal antibody. Western Blot analysis of TBL2 expression in human kidney.)

Western Blot (WB)

(Western Blot analysis of TBL2 expression in transfected 293T cell line by TBL2 polyclonal antibody. Lane 1: TBL2 transfected lysate (49.8kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-TBL2 antibody

TBL2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of TBL2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.

Product Categories/Family for anti-TBL2 antibody

Antibodies; Disease Markers

NCBI and Uniprot Product Information

• NCBI GI #: 7549793
• NCBI GeneID: 26608
• NCBI Accession #: NP_036585.1
• NCBI GenBank Nucleotide #: NM_012453.2
• Molecular Weight: 49,798 Da
• NCBI Official Full Name: transducin beta-like protein 2
• NCBI Official Synonym Full Names: transducin (beta)-like 2
• NCBI Official Symbol: TBL2
• NCBI Official Synonym Symbols: WBSCR13; WS-betaTRP
• NCBI Protein Information: transducin beta-like protein 2; WS beta-transducin repeats protein; Williams-Beuren syndrome chromosome region 13
• Protein Family: Transducin beta-like protein

NCBI Description

This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008]