Rabbit anti-Human, Mouse HLA-DMA Polyclonal Antibody | anti-HLA-DMA antibody

HLA-DMA (HLA Class II Histocompatibility Antigen, DM alpha Chain, MHC Class II Antigen DMA, Really Interesting New Gene 6 Protein, DMA, RING6) (FITC)

Cat. Num. AAA6381224

• Gene Names: HLA-DMA; DMA; HLADM; RING6; D6S222E
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: HLA-DMA; Polyclonal Antibody; HLA-DMA (HLA Class II Histocompatibility Antigen; DM alpha Chain; MHC Class II Antigen DMA; Really Interesting New Gene 6 Protein; DMA; RING6) (FITC); anti-HLA-DMA antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human HLA-DMA. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-HLA-DMA antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human HLA-DMA, aa1-261 (NP_006111.2).
• Immunogen Sequence: MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD
• Conjugate: FITC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(HLA-DMA rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in mouse kidney.)

Western Blot (WB)

(HLA-DMA rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in HeLa.)

Western Blot (WB)

(Western Blot analysis of HLA-DMA expression in transfected 293T cell line by HLA-DMA polyclonal antibody. Lane 1: HLA-DMA transfected lysate (29.2kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-HLA-DMA antibody

Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Product Categories/Family for anti-HLA-DMA antibody

Antibodies; HLA

NCBI and Uniprot Product Information

• NCBI GI #: 18765715
• NCBI GeneID: 3108
• NCBI Accession #: NP_006111.2
• NCBI GenBank Nucleotide #: NM_006120
• UniProt Accession #: P28067; Q29639; Q29640
• Molecular Weight: 29,194 Da
• NCBI Official Full Name: HLA class II histocompatibility antigen, DM alpha chain
• NCBI Official Synonym Full Names: major histocompatibility complex, class II, DM alpha
• NCBI Official Symbol: HLA-DMA
• NCBI Official Synonym Symbols: DMA; HLADM; RING6; D6S222E
• NCBI Protein Information: HLA class II histocompatibility antigen, DM alpha chain; MHC class II antigen DMA; really interesting new gene 6 protein; class II histocompatibility antigen, M alpha chain
• UniProt Protein Name: HLA class II histocompatibility antigen, DM alpha chain
• Protein Family: HLA class II histocompatibility antigen
• UniProt Gene Name: HLA-DMA
• UniProt Synonym Gene Names: DMA; RING6
• UniProt Entry Name: DMA_HUMAN