Rabbit anti-Human ACP2 Polyclonal Antibody | anti-ACP2 antibody

ACP2 (Lysosomal Acid Phosphatase, LAP) APC

Cat. Num. AAA6368605

• Gene Names: ACP2; LAP
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ACP2; Polyclonal Antibody; ACP2 (Lysosomal Acid Phosphatase; LAP) APC; anti-ACP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ACP2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 2111

• Applicable Applications for anti-ACP2 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human ACP2, aa1-423 (AAH03160.1).
• Immunogen Sequence: MAGKRSGWSRAALLQLLLGVNLVVMPPTQARSLRFVTLLYRHGDRSPVKTYPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVADGEDHA
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of ACP2 expression in transfected 293T cell line by ACP2 polyclonal antibody. Lane 1: ACP2 transfected lysate (48.3kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-ACP2 antibody

The ACP2 gene encodes lysosomal acid phosphatase-2 (EC 3.1.3.2), an enzyme with an acidic pH optimum that is expressed in the lysosomal compartment. Lysosomal acid phosphatase, which is found in all tissues, played a pivotal role in the discovery of lysosomes and is widely used as a biochemical marker for lysosomes.

Product Categories/Family for anti-ACP2 antibody

Antibodies; Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 13111974
• NCBI GeneID: 53
• NCBI Official Full Name: Homo sapiens acid phosphatase 2, lysosomal, mRNA
• NCBI Official Synonym Full Names: acid phosphatase 2, lysosomal
• NCBI Official Symbol: ACP2
• NCBI Official Synonym Symbols: LAP
• NCBI Protein Information: lysosomal acid phosphatase
• Protein Family: Cysteine proteinase

NCBI Description

The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]