BP-1 Recombinant Protein
BP-1, Recombinant, Human (Ly-51, 6C3)
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 35kD
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 35kD
Stability: Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.
NCBI and Uniprot Product Information
Uniprot Description
Pore-forming protein that forms cation-selective hydrophilic pores of around 1 nm and causes hemolysis. Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of several monomers (). This protein shows potent hemolytic activity (EC(50)=8.8 ng/ml) that is specifically inhibited by sphingomyelin. Shows no phospholipase A2 activity, nor antimicrobial activity against the four bacteria tested. Is lethal to crayfish (Ref. 1).
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Product Notes
The BP-1 (Catalog #AAA636816) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. ELISA, Inhibition Assays, Western Blotting. Researchers should empirically determine the suitability of the BP-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BP-1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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