Rabbit anti-Human TPGS2 Polyclonal Antibody | anti-TPGS2 antibody

TPGS2, ID (TPGS2, Tubulin polyglutamylase complex subunit 2) (Azide free) (HRP)

Cat. Num. AAA6357619

• Gene Names: TPGS2; L17; PGs2; C18orf10; HMFN0601
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TPGS2; Polyclonal Antibody; ID (TPGS2; Tubulin polyglutamylase complex subunit 2) (Azide free) (HRP); Tubulin polyglutamylase complex subunit 2; anti-TPGS2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-TPGS2 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:50-100; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: TPGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of human TPGS2.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TPGS2 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TPGS2 antibody detected the TPGS2 protein (arrow).)

Immunohistochemistry (IHC)

(TPGS2 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TPGS2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Product Categories/Family for anti-TPGS2 antibody

Antibodies; Tubulin

References

Petroziello, J., et al. Oncogene 23(46):7734-7745(2004). Yamada, S., et al. Oncogene 23(35):5901-5911(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 68534957
• NCBI GeneID: 25941
• NCBI Accession #: NP_056291.2
• NCBI GenBank Nucleotide #: NM_015476.3
• UniProt Accession #: Q68CL5; Q4KN59; Q8WTU3; Q96BT9; Q9Y435; B4DIX2; K7EIJ9
• Molecular Weight: 34,399 Da
• NCBI Official Full Name: tubulin polyglutamylase complex subunit 2 isoform 1
• NCBI Official Synonym Full Names: tubulin polyglutamylase complex subunit 2
• NCBI Official Symbol: TPGS2
• NCBI Official Synonym Symbols: L17; PGs2; C18orf10; HMFN0601
• NCBI Protein Information: tubulin polyglutamylase complex subunit 2
• UniProt Protein Name: Tubulin polyglutamylase complex subunit 2
• Protein Family: Tubulin polyglutamylase complex
• UniProt Gene Name: TPGS2
• UniProt Synonym Gene Names: C18orf10; PGs2
• UniProt Entry Name: TPGS2_HUMAN

NCBI Description

This gene encodes a protein that is a component of the neuronal polyglutamylase complex, which plays a role in post-translational addition of glutamate residues to C-terminal tubulin tails. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]

Uniprot Description

TPGS2: 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q12.2

Cellular Component: microtubule; cytoplasm