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Plasminogen Activator Inhibitor Type 1, NBD P9 mutant Protein

Plasminogen Activator Inhibitor Type 1, NBD P9 mutant, Human (PAI-1)

Purity
Highly Purified
>98% pure by SDS PAGE.
Synonyms
Plasminogen Activator Inhibitor Type 1; NBD P9 mutant; Human (PAI-1); NBD P9 mutant protein
Ordering
For Research Use Only!
Purity/Purification
Highly Purified
>98% pure by SDS PAGE.
Solubility
>2mg/ml and <5mg/ml
Preparation and Storage
Store frozen at -70 degree C - stability >1 year
Related Product Information for Plasminogen Activator Inhibitor Type 1, NBD P9 mutant protein
Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma that is implicated in the processes of angiogenesis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation (1). The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer (2,3,4). PAI-1 is activated by the glycoprotein vitronectin. Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration (5). This binding has proven to be an important inhibitor of the activated form of protein C (APC) (6).
Product Categories/Family for Plasminogen Activator Inhibitor Type 1, NBD P9 mutant protein

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Product Notes

The Plasminogen Activator Inhibitor Type 1, NBD P9 mutant (Catalog #AAA634938) is a Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Plasminogen Activator Inhibitor Type 1, NBD P9 mutant, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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