Rabbit anti-Human SDF4 Polyclonal Antibody | anti-SDF4 antibody

SDF4, CT (SDF4, CAB45, 45kD calcium-binding protein, Stromal cell-derived factor 4) (FITC)

Cat. Num. AAA6345616

• Gene Names: SDF4; Cab45; SDF-4
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SDF4; Polyclonal Antibody; CT (SDF4; CAB45; 45kD calcium-binding protein; Stromal cell-derived factor 4) (FITC); Stromal cell-derived factor 4; anti-SDF4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-SDF4 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: SDF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-287 amino acids from the C-terminal region of human SDF4.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SDF4 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SDF4 antibody detected the SDF4 protein (arrow).)

Related Product Information for anti-SDF4 antibody

SDF4 may regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment (By similarity). Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

Product Categories/Family for anti-SDF4 antibody

Antibodies; Binding Proteins; Calcium

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Kang, H., et al. Int. J. Oncol. 35(1):205-211(2009). Zhu, Y., et al. J Genet Genomics 35(3):153-161(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 7706573
• NCBI GeneID: 51150
• NCBI Accession #: NP_057631.1; NP_057260.2
• NCBI GenBank Nucleotide #: NM_016547.2
• UniProt Accession #: Q9BRK5; Q53G52; Q53HQ9; Q8NBQ3; Q96AA1; Q9NZP7; Q9UN53; B1AME5; B1AME6; B2RDF1; B4DSM1
• Molecular Weight: 39,608 Da
• NCBI Official Full Name: 45 kDa calcium-binding protein isoform 1
• NCBI Official Synonym Full Names: stromal cell derived factor 4
• NCBI Official Symbol: SDF4
• NCBI Official Synonym Symbols: Cab45; SDF-4
• NCBI Protein Information: 45 kDa calcium-binding protein
• UniProt Protein Name: 45 kDa calcium-binding protein
• Protein Family: 45 kDa calcium-binding protein
• UniProt Gene Name: SDF4
• UniProt Synonym Gene Names: CAB45; Cab45; SDF-4
• UniProt Entry Name: CAB45_HUMAN

NCBI Description

This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011]

Uniprot Description

SDF4: May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. Belongs to the CREC family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 1p36.33

Cellular Component: Golgi apparatus; membrane; Golgi lumen; cytoplasm; late endosome; plasma membrane

Molecular Function: identical protein binding; protein binding; calcium ion binding

Biological Process: fat cell differentiation; response to ethanol; UV protection; cerebellum development; calcium ion-dependent exocytosis