Rabbit anti-Human S6A12 Polyclonal Antibody | anti-S6A12 antibody
S6A12, NT (SLC6A12, Sodium-and chloride-dependent betaine transporter, BGT-1, Na(+)/Cl(-) betaine/GABA transporter, Solute carrier family 6 member 12) (MaxLight 490)
Gene Names
SLC6A12; BGT1; GAT2; BGT-1
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
S6A12; Polyclonal Antibody; NT (SLC6A12; Sodium-and chloride-dependent betaine transporter; BGT-1; Na(+)/Cl(-) betaine/GABA transporter; Solute carrier family 6 member 12) (MaxLight 490); SLC6A12; Solute carrier family 6 member 12; anti-S6A12 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-S6A12 antibody
Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)
Application Notes
FC/FACS: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
S6A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human S6A12.
Conjugate
MaxLight490
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for anti-S6A12 antibody
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Product Categories/Family for anti-S6A12 antibody
References
Pasaje, C.F., et al. Ann. Hum. Genet. 74(4):326-334(2010). Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010). Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010): Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009). Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,368 Da
NCBI Official Full Name
sodium- and chloride-dependent betaine transporter
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter), member 12
NCBI Official Symbol
SLC6A12
NCBI Official Synonym Symbols
BGT1; GAT2; BGT-1
NCBI Protein Information
sodium- and chloride-dependent betaine transporter; betaine/GABA transporter-1; gamma-aminobutyric acid transporter; Na(+)/Cl(-) betaine/GABA transporter; solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
UniProt Protein Name
Sodium- and chloride-dependent betaine transporter
UniProt Gene Name
SLC6A12
UniProt Entry Name
S6A12_HUMAN
Uniprot Description
SLC6A12: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: gamma-aminobutyric acid:sodium symporter activity; neurotransmitter:sodium symporter activity
Biological Process: response to organic substance; synaptic transmission; cellular water homeostasis; transport; amino acid transport; neurotransmitter secretion; ion transport; transmembrane transport; gamma-aminobutyric acid transport
Research Articles on S6A12
Similar Products
Product Notes
The S6A12 slc6a12 (Catalog #AAA6344805) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The S6A12, NT (SLC6A12, Sodium-and chloride-dependent betaine transporter, BGT-1, Na(+)/Cl(-) betaine/GABA transporter, Solute carrier family 6 member 12) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's S6A12 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), FLISA, Western Blot (WB). FC/FACS: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the S6A12 slc6a12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S6A12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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