Rabbit anti-Human RELT Polyclonal Antibody | anti-RELT antibody

RELT, CT (RELT, TNFRSF19L, Tumor necrosis factor receptor superfamily member 19L, Receptor expressed in lymphoid tissues) (Biotin)

Cat. Num. AAA6341303

• Gene Names: RELT; TRLT; TNFRSF19L
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RELT; Polyclonal Antibody; CT (RELT; TNFRSF19L; Tumor necrosis factor receptor superfamily member 19L; Receptor expressed in lymphoid tissues) (Biotin); Receptor expressed in lymphoid tissues; anti-RELT antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-RELT antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: RELT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-413 amino acids from the C-terminal region of human RELT.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(RELT Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the RELT antibody detected the RELT protein (arrow).)

Related Product Information for anti-RELT antibody

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Product Categories/Family for anti-RELT antibody

Antibodies; Receptors

References

Cusick, J.K., et al. Cell. Immunol. 261(1):1-8(2010). Polek, T.C., et al. Biochem. Biophys. Res. Commun. 349(3):1016-1024(2006). Bossen, C., et al. J. Biol. Chem. 281(20):13964-13971(2006). Cusick, J.K., et al. Biochem. Biophys. Res. Commun. 340(2):535-543(2006). Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 23238200
• NCBI GeneID: 84957
• NCBI Accession #: NP_689408.1; NP_116260.2
• NCBI GenBank Nucleotide #: NM_152222.1
• UniProt Accession #: Q969Z4; Q86V34; Q96JU1; Q9BUX7
• Molecular Weight: 46,092 Da
• NCBI Official Full Name: tumor necrosis factor receptor superfamily member 19L
• NCBI Official Synonym Full Names: RELT tumor necrosis factor receptor
• NCBI Official Symbol: RELT
• NCBI Official Synonym Symbols: TRLT; TNFRSF19L
• NCBI Protein Information: tumor necrosis factor receptor superfamily member 19L; receptor expressed in lymphoid tissues
• UniProt Protein Name: Tumor necrosis factor receptor superfamily member 19L
• Protein Family: RELT-like protein
• UniProt Gene Name: RELT
• UniProt Synonym Gene Names: TNFRSF19L
• UniProt Entry Name: TR19L_HUMAN

Uniprot Description

RELT: Mediates activation of NF-kappa-B. May play a role in T- cell activation. Belongs to the RELT family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13.4

Cellular Component: cytoplasm; integral to membrane; plasma membrane