Rabbit anti-Mouse PQLC2 Polyclonal Antibody | anti-PQLC2 antibody

PQLC2, CT (PQLC2, PQ-loop repeat-containing protein 2) (Biotin)

Cat. Num. AAA6336843

• Gene Names: SLC66A1; LAAT1; PQLC2; LAAT-1
• Reactivity: Mouse
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: PQLC2; Polyclonal Antibody; CT (PQLC2; PQ-loop repeat-containing protein 2) (Biotin); PQ-loop repeat-containing protein 2; anti-PQLC2 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 291

• Applicable Applications for anti-PQLC2 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: PQLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-251 amino acids from the C-terminal region of human PQLC2.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PQLC2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the PQLC2 antibody detected the PQLC2 protein (arrow).)

Immunohistochemistry (IHC)

(PQLC2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PQLC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-PQLC2 antibody

The specific function of this protein remains unknown. There are 3 named isoforms.

Product Categories/Family for anti-PQLC2 antibody

Antibodies; Proteins

References

Gregory, S.G., et al. Nature 441(7091):315-321(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 92110025
• NCBI GeneID: 54896
• NCBI Accession #: NP_060235.2; NP_001035214.1
• NCBI GenBank Nucleotide #: NP_060235.2
• UniProt Accession #: Q6ZP29
• NCBI Official Full Name: lysosomal amino acid transporter 1 homolog isoform 1
• NCBI Official Synonym Full Names: solute carrier family 66 member 1
• NCBI Official Symbol: SLC66A1
• NCBI Official Synonym Symbols: LAAT1; PQLC2; LAAT-1
• NCBI Protein Information: lysosomal amino acid transporter 1 homolog
• UniProt Protein Name: Lysosomal amino acid transporter 1 homolog
• Protein Family: Lysosomal amino acid transporter
• UniProt Gene Name: PQLC2

Uniprot Description

PQLC2: Lysosomal lysine/arginine transporter that specifically mediates the export of lysine and arginine from lysosomes. Belongs to the laat-1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane

Molecular Function: arginine transmembrane transporter activity; basic amino acid transmembrane transporter activity; L-lysine transmembrane transporter activity

Biological Process: arginine transport; lysine transport; transmembrane transport