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Western Blot (WB) (PNMA3 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PNMA3 antibody detected the PNMA3 protein (arrow).)

Rabbit anti-Human PNMA3 Polyclonal Antibody | anti-PNMA3 antibody

PNMA3, CT (PNMA3, MA3, Paraneoplastic antigen Ma3) (PE)

Gene Names
PNMA3; MA3; MA5
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PNMA3; Polyclonal Antibody; CT (PNMA3; MA3; Paraneoplastic antigen Ma3) (PE); Paraneoplastic antigen Ma3; anti-PNMA3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Sequence Length
463
Applicable Applications for anti-PNMA3 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of human PNMA3.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PNMA3 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PNMA3 antibody detected the PNMA3 protein (arrow).)

Western Blot (WB) (PNMA3 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PNMA3 antibody detected the PNMA3 protein (arrow).)
Product Categories/Family for anti-PNMA3 antibody
References
Wills, N.M., et al. J. Biol. Chem. 281(11):7082-7088(2006). Schuller, M., et al. J. Neuroimmunol. 169 (1-2), 172-176 (2005): Rosenfeld, M.R., et al. Ann. Neurol. 50(3):339-348(2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
paraneoplastic antigen Ma3
NCBI Official Synonym Full Names
PNMA family member 3
NCBI Official Symbol
PNMA3
NCBI Official Synonym Symbols
MA3; MA5
NCBI Protein Information
paraneoplastic antigen Ma3
UniProt Protein Name
Paraneoplastic antigen Ma3
Protein Family
UniProt Gene Name
PNMA3
UniProt Synonym Gene Names
MA3
UniProt Entry Name
PNMA3_HUMAN

NCBI Description

The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Uniprot Description

PNMA3: a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. [provided by RefSeq, Jul 2008]

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: nucleolus

Molecular Function: nucleic acid binding; zinc ion binding

Biological Process: positive regulation of apoptosis

Research Articles on PNMA3

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Product Notes

The PNMA3 pnma3 (Catalog #AAA6335322) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PNMA3, CT (PNMA3, MA3, Paraneoplastic antigen Ma3) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PNMA3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PNMA3 pnma3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PNMA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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