Rabbit anti-Human LETM1 Polyclonal Antibody | anti-LETM1 antibody

LETM1, CT (LETM1, LETM1 and EF-hand domain-containing protein 1, mitochondrial, Leucine zipper-EF-hand-containing transmembrane protein 1) (APC)

Cat. Num. AAA6315735

• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LETM1; Polyclonal Antibody; CT (LETM1; LETM1 and EF-hand domain-containing protein 1; mitochondrial; Leucine zipper-EF-hand-containing transmembrane protein 1) (APC); Leucine zipper-EF-hand-containing transmembrane protein 1; anti-LETM1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-LETM1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-607 amino acids from the C-terminal region of human LETM1.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(LETM1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the LETM1 antibody detected the LETM1 protein (arrow).)

Related Product Information for anti-LETM1 antibody

This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.

Product Categories/Family for anti-LETM1 antibody

Antibodies; Transmembrane Proteins

References

Jiang, D., et al. Science 326(5949):144-147(2009). Piao, L., et al. Cell. Signal. 21(5):767-777(2009). Piao, L., et al. Cancer Res. 69(8):3397-3404(2009). Tamai, S., et al. J. Cell. Sci. 121 (PT 15), 2588-2600 (2008): Dimmer, K.S., et al. Hum. Mol. Genet. 17(2):201-214(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 6912482
• NCBI GeneID: 3954
• NCBI Accession #: NP_036450.1
• NCBI GenBank Nucleotide #: NM_012318.2
• UniProt Accession #: O95202; Q9UF65; B4DED2
• Molecular Weight: 83,354 Da
• NCBI Official Full Name: LETM1 and EF-hand domain-containing protein 1, mitochondrial
• NCBI Official Synonym Full Names: leucine zipper-EF-hand containing transmembrane protein 1
• NCBI Official Symbol: LETM1
• NCBI Protein Information: LETM1 and EF-hand domain-containing protein 1, mitochondrial; Mdm38 homolog; leucine zipper-EF-hand-containing transmembrane protein 1
• UniProt Protein Name: LETM1 and EF-hand domain-containing protein 1, mitochondrial
• Protein Family: LETM1 domain-containing protein
• UniProt Gene Name: LETM1
• UniProt Entry Name: LETM1_HUMAN