Rabbit Jun D Polyclonal Antibody | anti-JUN antibody

Jun D, phosphorylated (Ser255) (Transcription Factor Jun-D, JUND)

Cat. Num. AAA630819

• Gene Names: JUN; AP1; AP-1; c-Jun
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Jun D; Polyclonal Antibody; phosphorylated (Ser255) (Transcription Factor Jun-D; JUND); Anti -Jun D; anti-JUN antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human Jun D when phosphorylated at serine 255. Species Cross-Reactivity: mouse, rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.

• Applicable Applications for anti-JUN antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot and Immunohistochemistry.; Dilution: Western Blot:1:500-1:1,000; Immunohistochemistry:1:50-1:100
• Immunogen: Synthetic non-phosphopeptide corresponding to human JunD around the phosphorylation site of serine 255 (G-E-SP-P-P).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-JUN antibody

JunD is a member of the JUN family, and a functional component of the AP1 transcription factor complex. JunD binds an AP-1 site and upon cotransfection stimulates the activity of a promoter that bears an AP-1 site. It also binds DNA as a dimer. Furthermore, JunD has been proposed to protect cells from p53-dependent senescence and apoptosis.

Product Categories/Family for anti-JUN antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 49456463
• NCBI GeneID: 3725
• UniProt Accession #: Q6FHK0; P05412
• Molecular Weight: 35,724 Da
• NCBI Official Full Name: JUN
• NCBI Official Synonym Full Names: jun proto-oncogene
• NCBI Official Symbol: JUN
• NCBI Official Synonym Symbols: AP1; AP-1; c-Jun
• NCBI Protein Information: transcription factor AP-1; p39; jun oncogene; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog
• UniProt Protein Name: JUN protein
• Protein Family: Jun dimerization protein
• UniProt Gene Name: JUN
• UniProt Entry Name: Q6FHK0_HUMAN

NCBI Description

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]