Testing Data
Rabbit anti-Human IKK alpha, C1 Polyclonal Antibody
IKK alpha, C1 (Ika Kinase)
Reactivity
Human
Applications
Western Blot
Purity
PurifiedPurified by immunoaffinity chromatography.
Synonyms
IKK alpha; C1; Polyclonal Antibody; C1 (Ika Kinase); Anti -IKK alpha; anti-IKK alpha; C1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Detects an 85kD band. Does not crossreact with IKKb or IKKg.
Purity/Purification
Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide, before the addition of glycerol to 40%.
Applicable Applications for anti-IKK alpha, C1 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 1:500-1:1000
Dilution: Western Blot: 1:500-1:1000
Immunogen
Peptide corresponding to aa716-734 of human IKKa (1,2). Differs from corresponding murine sequence by four amino acids.
Positive Control
Whole cell lysate from HeLa or Jurkat cells.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Testing Data
Testing Data
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-IKK alpha, C1 antibody
Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, and bacteria product LPS. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. The long-sought IkB kinase (IKK), which phosphorylates IkB, and mediates IkB degradation and NF-kB activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKKa and IKKb). IKKa and IKKb interact with each other and both are essential for the NF-kB activation. IKKa specifically phosphorylates IkB-a. IKKa is expressed in variety of human tissues.
Product Categories/Family for anti-IKK alpha, C1 antibody
Similar Products
Product Notes
The IKK alpha, C1 (Catalog #AAA629985) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IKK alpha, C1 (Ika Kinase) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IKK alpha, C1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 1:500-1:1000. Researchers should empirically determine the suitability of the IKK alpha, C1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKK alpha, C1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
