Rabbit anti-Human CPNE5 Polyclonal Antibody | anti-CPNE5 antibody

CPNE5, CT (CPNE5, KIAA1599, Copine-5, Copine V) (Azide free) (HRP)

Cat. Num. AAA6288344

• Gene Names: CPNE5; CPN5; COPN5
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CPNE5; Polyclonal Antibody; CT (CPNE5; KIAA1599; Copine-5; Copine V) (Azide free) (HRP); Copine V; anti-CPNE5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-CPNE5 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CPNE5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-535 amino acids from the C-terminal region of human CPNE5.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CPNE5 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CPNE5 antibody detected the CPNE5 protein (arrow).)

Related Product Information for anti-CPNE5 antibody

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Sequence analysis identified multiple alternatively spliced transcript variants but their full-length natures could not be determined.

Product Categories/Family for anti-CPNE5 antibody

Antibodies; KIAA; orf

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Mungall, A.J., et al. Nature 425(6960):805-811(2003). Tripodis, N., et al. Genome Res. 8(6):631-643(1998). Creutz, C.E., et al. J. Biol. Chem. 273(3):1393-1402(1998).

NCBI and Uniprot Product Information

• NCBI GI #: 25141323
• NCBI GeneID: 57699
• NCBI Accession #: NP_065990.1
• NCBI GenBank Nucleotide #: NM_020939.1
• UniProt Accession #: Q9HCH3; Q7Z6C8
• Molecular Weight: 32,627 Da
• NCBI Official Full Name: copine-5 isoform a
• NCBI Official Synonym Full Names: copine 5
• NCBI Official Symbol: CPNE5
• NCBI Official Synonym Symbols: CPN5; COPN5
• NCBI Protein Information: copine-5
• UniProt Protein Name: Copine-5
• Protein Family: Copine
• UniProt Gene Name: CPNE5

NCBI Description

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. More variants may exist, but their full-length natures could not be determined. [provided by RefSeq, Sep 2015]

Uniprot Description

Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (). Plays a role in dendrite formation by melanocytes (PubMed:23999003).