Rabbit anti-Human tch homolog 4, Drosophila, INT3) Polyclonal Antibody
tch homolog 4, Drosophila, INT3)
Reactivity
Human
Applications
ELISA
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
tch homolog 4; Drosophila; INT3); Polyclonal Antibody; Anti -tch homolog 4; anti-tch homolog 4; INT3) antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Notch 4
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide, before the addition of glycerol to 40%.
Applicable Applications for anti-tch homolog 4, Drosophila, INT3) antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Dilution: ELISA: 1:500 by peptide-specific ELISA
Dilution: ELISA: 1:500 by peptide-specific ELISA
Immunogen
Synthetic peptide (KLH coupled) comprised of amino acids 1984-2002 [CGPPALQEMPINQGGEGKK] of the human NOTCH homolog 4 (NOTCH4) protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-tch homolog 4, Drosophila, INT3) antibody
Notch signaling plays a key role in the normal development of many tissues and cell types, through diverse effects on differentiation, survival, and/or proliferation that are highly dependent on signal strength and cellular context. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Notch family members share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Multiple human notch proteins (Notch1, Notch2, Notch3 and Notch4) have been identified and they function as a receptors for membrane bound ligands. Notch signaling is also linked to tumorigenesis as first demonstrated by the identification of a recurrent t(7;9)(q34;q34.3) chromosomal translocation involving the human Notch1 gene that is found in a small subset of human pre-T-cell acute lymphoblastic leukemias (T-ALL). Since this discovery, aberrant Notch signaling has been suggested to be involved in a wide variety of human neoplasms. Notch4 functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Notch4 may also be associated with susceptibility to schizophrenia in a small portion of cases.
Product Categories/Family for anti-tch homolog 4, Drosophila, INT3) antibody
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Product Notes
The tch homolog 4, Drosophila, INT3) (Catalog #AAA626933) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The tch homolog 4, Drosophila, INT3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's tch homolog 4, Drosophila, INT3) can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: ELISA: 1:500 by peptide-specific ELISA. Researchers should empirically determine the suitability of the tch homolog 4, Drosophila, INT3) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "tch homolog 4, Drosophila, INT3), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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