Mouse Collagen Type VII Monoclonal Antibody
Collagen Type VII (BSA & Azide Free) (PE)
Reactivity
Bovine, Goat, Guinea Pig, Human, Monkey, Sheep
Applications
ELISA, Immunofluorescence, Immunohistochemistry
Purity
Purified by Protein G Affinity Chromatography
Synonyms
Collagen Type VII; Monoclonal Antibody; Collagen Type VII (BSA & Azide Free) (PE); anti-Collagen Type VII antibody
Host
Mouse
Reactivity
Bovine, Goat, Guinea Pig, Human, Monkey, Sheep
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
0.N.229
Specificity
Recognizes intact (250kD) and collagenase digested (150kD) tissue Type VII collagen. It reacts with the basement membrane zone of stratified squamous epithelia. Does not crossreact with types I, II, III, IV, V collagens, lamins and fibronectin. Epitope: Located on non-helical (non-collagenous) C-terminal region of collagen VII and is resistant to collagenase, trypsin, pronase, neuraminidase, chondroitinase, and hyaluronidase However, it is lost by digestion of collagen VII with pepsin. Species Crossreactivity: Human, marmoset, monkey, bovine, sheep, goat, porcine and guinea pig.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-Collagen Type VII antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC)
Immunogen
Insoluble fractions of human neonatal foreskin epidermal cells. Cellular Localization: Epidermal basement membrane. MW: Intact: 250kD; Digested: 150kD.
Conjugate
PE
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-Collagen Type VII antibody
References
1. Leigh, I.M., et al., Epithelia 1:17-29 (1987). 2. Burge, S., et al., Brit. J. Dermatol. 118:629-640 (1988). 3. Heagerty. A.H., et al., Journal of Investigative Dermatology 86(5):603-5 (1986). 4. Leigh, I.M., et al., Dermatology 90(5):639-42 (1988). 5. Kirkham, N., et al., Journal of Pathology 157(3):243-7 (1989). 6. Tatnall, F.M., et al., British Journal of Dermatology 120(4):533-9 (1989). 7. Shimizu, H., et al., British Journal of Dermatology 122(5):577-85 (1990). 8. Wetzels, R.H., et al., Journal of Pathology 139(2):451-9 (1991).
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Product Notes
The Collagen Type VII (Catalog #AAA6266888) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Collagen Type VII (BSA & Azide Free) (PE) reacts with Bovine, Goat, Guinea Pig, Human, Monkey, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Collagen Type VII can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the Collagen Type VII for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collagen Type VII, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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