Fibroblast Growth Factor 16 Recombinant Protein | FGF16 recombinant protein

Fibroblast Growth Factor 16, Recombinant, Human (FGF16)

Cat. Num. AAA625511

• Gene Names: FGF16; FGF-16
• Reactivity: Human
• Purity: Affinity Purified; Purified by affinity chromatography employing immobilized hFGF-16 matrix.
• Synonyms: Fibroblast Growth Factor 16; Polyclonal Recombinant Protein; Recombinant; Human (FGF16); Anti -Fibroblast Growth Factor 16; FGF16 recombinant protein

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human Fibroblast Growth Factor 16.
• Purity/Purification: Affinity Purified; Purified by affinity chromatography employing immobilized hFGF-16 matrix.
• Form/Format: Supplied as a sterile-filtered lyophilized powder in 0.5X PBS, pH 7.4, 0.1% sodium azide. When reconstituted in sterile water to a concentration of >0.2mg/ml the antibody is stable for at least six weeks at 2-4 degree C.

• Application Notes: Suitable for use in ELISA.; Dilution: ELISA: > 0.5ug/ml using 100ul/well detects of 0.2-0.4 ng/well of recombinant hFGF-16.; Western Blot: 0.1-0.2ug/ml detects hFGF-16 in conjunction with compatible secondary reagents. The detection limit for recombinant hFGF-16 is 1.5-3.0ng/lane, under either reducing or non-reducing conditions.
• Immunogen: Highly purified recombinant hFGF-16 (human Fibroblast Growth Factor-16)
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for FGF16 recombinant protein

Fibroblast Growth Factor 16 (FGF16) play a key role in controlling tissue growth, morphogenesis and repair in animals. FGF-16 is a newly discovered heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. Recombinant Human FGF-16 is a 23.7kD protein containing 207 amino residues.

Product Categories/Family for FGF16 recombinant protein

Antibodies; Abs to Growth Factors; Cytokines

NCBI and Uniprot Product Information

• NCBI GI #: 4503691
• NCBI GeneID: 8823
• NCBI Accession #: NP_003859.1
• NCBI GenBank Nucleotide #: NM_003868.1
• UniProt Accession #: O43320; Q5HY72
• Molecular Weight: 23,759 Da
• NCBI Official Full Name: fibroblast growth factor 16
• NCBI Official Synonym Full Names: fibroblast growth factor 16
• NCBI Official Symbol: FGF16
• NCBI Official Synonym Symbols: FGF-16
• NCBI Protein Information: fibroblast growth factor 16; OTTHUMP00000015342
• UniProt Protein Name: Fibroblast growth factor 16
• Protein Family: Fibroblast growth factor
• UniProt Gene Name: FGF16
• UniProt Entry Name: FGF16_HUMAN

NCBI Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity, which suggests a role in proliferation of embryonic brown adipose tissue. [provided by RefSeq]

Uniprot Description

FGF16: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: Xq13

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; regulation of endothelial cell proliferation; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; metabolic process; signal transduction; response to temperature stimulus; organ morphogenesis; cell-cell signaling; regulation of MAP kinase activity; insulin receptor signaling pathway; innate immune response

Disease: Metacarpal 4-5 Fusion