Testing Data
(Whole rat brain preparations were resolved by electrophoresis, transferred to nitrocellulose and probed with P9109-27Y (1:5000 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. STEP isoforms detected at Mr ~64-66 (doublet), 46 and 38kD.)
Mouse anti-Mouse, Rat Protein Tyrosine Phosphatase, Non-receptor Type 5 Monoclonal Antibody | anti-PTPN5 antibody
Protein Tyrosine Phosphatase, Non-receptor Type 5 (PTPN5, Striatum-Enriched Protein-Tyrosine Phosphatase, STEP, Striatal enriched phosphatase, FLJ14427) (FITC)
Gene Names
Ptpn5; STEP
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
Protein Tyrosine Phosphatase; Non-receptor Type 5; Monoclonal Antibody; Non-receptor Type 5 (PTPN5; Striatum-Enriched Protein-Tyrosine Phosphatase; STEP; Striatal enriched phosphatase; FLJ14427) (FITC); anti-PTPN5 antibody
Host
Mouse
Reactivity
Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
5H41
Specificity
Recognizes rat STEP61, STEP46, STEP38 and STEP20, Mr ~64-66 (doublet), 46 and 38kD. Additional isoforms may be detected with higher concentrations of cell lysates and/or antibody. Species Crossreactivity: rmouse.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Applicable Applications for anti-PTPN5 antibody
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Synthetic peptide corresponding to aa57-74 MCTPGCNEEGFGYLVSPR, of rat STEP46 conjugated to KLH. Species Sequence Homology: Mouse (100%), human (94%)
Conjugate
FITC
Preparation and Storage
Store at -20 degree C.
Testing Data
(Whole rat brain preparations were resolved by electrophoresis, transferred to nitrocellulose and probed with P9109-27Y (1:5000 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. STEP isoforms detected at Mr ~64-66 (doublet), 46 and 38kD.)
Testing Data
(Whole rat brain preparations were resolved by electrophoresis, transferred to nitrocellulose and probed with P9109-27Y (1:5000 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. STEP isoforms detected at Mr ~64-66 (doublet), 46 and 38kD.)
Product Categories/Family for anti-PTPN5 antibody
References
1. Lombroso, P.J., et al., Proc. Natl. Acad. Sci. 88:7242-7246, 1991. 2. Lombroso, P.J., et al., J. Neurosci. 13:3064-3074, 1993. 3. Nguyen, T.-H., et al., J. Neurochem. 73:1995-2001, 1999. 4. Nguyen, T.-H., et al., J. Biol. Chem. 277:24274-24279, 2002. 5. Boulanger, L.M., et al., J. Neurosci. 15:1532-1544, 1995.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,366 Da
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 5
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 5
NCBI Official Symbol
Ptpn5
NCBI Official Synonym Symbols
STEP
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 5; protein-tyrosine-phosphatase non-receptor 5; neural-specific protein-tyrosine phosphatase; protein-tyrosine phosphatase striatum-enriched; striatum-enriched protein-tyrosine phosphatase
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 5
Protein Family
UniProt Gene Name
Ptpn5
UniProt Synonym Gene Names
STEP
UniProt Entry Name
PTN5_RAT
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Product Notes
The PTPN5 ptpn5 (Catalog #AAA6243493) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Protein Tyrosine Phosphatase, Non-receptor Type 5 (PTPN5, Striatum-Enriched Protein-Tyrosine Phosphatase, STEP, Striatal enriched phosphatase, FLJ14427) (FITC) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Protein Tyrosine Phosphatase, Non-receptor Type 5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the PTPN5 ptpn5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein Tyrosine Phosphatase, Non-receptor Type 5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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