Rabbit anti-Human FXR Polyclonal Antibody | anti-fxr antibody
FXR (Farnesoid X-activated Receptor, Bile Acid Receptor, BAR, HRR-1, Nuclear Receptor Subfamily 1 Group H Member 4, NR1H4, Retinoid X Receptor-interacting Protein 14, RXR-interacting Protein 14, RIP14)
Gene Names
fxr; fxr
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
FXR; Polyclonal Antibody; FXR (Farnesoid X-activated Receptor; Bile Acid Receptor; BAR; HRR-1; Nuclear Receptor Subfamily 1 Group H Member 4; NR1H4; Retinoid X Receptor-interacting Protein 14; RXR-interacting Protein 14; RIP14); Anti -FXR (Farnesoid X-activated Receptor; anti-fxr antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Species Crossreactivity: Human. Other species have not been tested.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in Tris-glycine, 150mM sodium chloride,, pH 7.2, 0.05% sodium azide.
Applicable Applications for anti-fxr antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
A synthetic peptide made to the C-terminus of the human FXR protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-fxr antibody
The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and bind DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, as well as several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed "orphan receptors" because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.
Product Categories/Family for anti-fxr antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
3,844 Da
NCBI Official Full Name
FXR
NCBI Official Synonym Full Names
farnesoid X-activated receptor
NCBI Official Symbol
fxr
NCBI Official Synonym Symbols
fxr
NCBI Protein Information
farnesoid X-activated receptor
UniProt Protein Name
FXR
UniProt Gene Name
fxr
UniProt Entry Name
O42540_DANRE
Similar Products
Product Notes
The fxr fxr (Catalog #AAA618940) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FXR (Farnesoid X-activated Receptor, Bile Acid Receptor, BAR, HRR-1, Nuclear Receptor Subfamily 1 Group H Member 4, NR1H4, Retinoid X Receptor-interacting Protein 14, RXR-interacting Protein 14, RIP14) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FXR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the fxr fxr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FXR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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