Mouse PNMA1 Monoclonal Antibody | anti-PNMA1 antibody
PNMA1 (Paraneoplastic Antigen MA1, MA1) (FITC)
FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors. [provided by RefSeq, Feb 2014]
Uniprot Description
PNMA1: Belongs to the PNMA family
Protein type: Nucleolus
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: focal adhesion; cytoplasm; nucleolus
Molecular Function: protein binding
Biological Process: inflammatory response to antigenic stimulus; positive regulation of apoptosis