anti-Rat Organic Anion Transporter K1 Polyclonal Antibody | anti-Slc21a4 antibody
Anti - Organic Anion Transporter K1 (OAT-K1)
Gene Names
Slc21a4; OAT-K1; OAT-K2; Slco1a3; rOAT-K1; rOAT-K2; rOAT-K3; rOAT-K5; rOAT-K6; rOAT-K7; rOAT-K8; rOAT-K9; rOAT-K11; rOAT-K13; rOAT-K14
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
Organic Anion Transporter K1; Polyclonal Antibody; Anti - Organic Anion Transporter K1 (OAT-K1); Organic Anion Transporter K1 (OAT-K1); anti-Slc21a4 antibody
Host
Host: Rabbit
Source: Rat
Source: Rat
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
The 16 AA rat control peptide is unique to rat OAT-K1. No significant sequence homology is detected with OAT-K2 or other OATs. The control peptide is available to confirm specificity of antibodies
Purity/Purification
Serum
Form/Format
Serum
Supplied as a liquid, neat serum, 40% glycerol.
Supplied as a liquid, neat serum, 40% glycerol.
Sequence Length
670
Applicable Applications for anti-Slc21a4 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA, Western Blotting. Other applications not tested.
Dilution: Western Blotting1:1000-1:5000 for neat serum and 1-10ug/ml for affinity pure antibody using ECL technique.
ELISA:1:10,000-50,000 for neat serum and 0.5-1ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Dilution: Western Blotting1:1000-1:5000 for neat serum and 1-10ug/ml for affinity pure antibody using ECL technique.
ELISA:1:10,000-50,000 for neat serum and 0.5-1ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Immunogen
A 14 AA Peptide sequence near the cytoplasmic, C-terminus of rat OAT-K1
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Slc21a4 antibody
Mammalian kidney and liver are critical in maintaining physiological ionic environment. Kidney specializes in removing toxins, drugs, and other organic anions from the blood by a process called "renal secretion". Besides kidney, anionic substrates are also transported in other organs, e.g., choroid plexus, eye, airway, and placenta. Several multispecific OATs (OAT1-3, OAT-K1 and OATK2) and OATPs (organic anion transporting polypeptides; oatp1-3), have been cloned and characterized from various tissues. OATPs family of proteins are very similar in sequence and secondary protein structure (up to 12 transmembrane domains with cytoplasmic N and C-terminus).
Product Categories/Family for anti-Slc21a4 antibody
References
• 1. Saito H et al (1996) J Biol. Chem. 271, 20719-20725; Masuda S et al (1997) FEBS Lett. 407, 127-131; Masuda S et al (1999) Mol. Pharmacol. 55, 743-752.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
73,817 Da
NCBI Official Full Name
organic anion transporter K1
NCBI Official Synonym Full Names
kidney specific organic anion transporter
NCBI Official Symbol
Slc21a4
NCBI Official Synonym Symbols
OAT-K1; OAT-K2; Slco1a3; rOAT-K1; rOAT-K2; rOAT-K3; rOAT-K5; rOAT-K6; rOAT-K7; rOAT-K8; rOAT-K9; rOAT-K11; rOAT-K13; rOAT-K14
NCBI Protein Information
solute carrier organic anion transporter family member 1A3; rOAT-K; solute carrier family 21 member 4; sodium-independent organic anion transporter K1
UniProt Protein Name
Solute carrier organic anion transporter family member 1A3
UniProt Gene Name
Slco1a3
UniProt Synonym Gene Names
Oatp1a3; Slc21a4
UniProt Entry Name
SO1A3_RAT
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Product Notes
The Slc21a4 slco1a3 (Catalog #AAA617082) is an Antibody produced from Host: Rabbit Source: Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti - Organic Anion Transporter K1 (OAT-K1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Organic Anion Transporter K1 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA, Western Blotting. Other applications not tested. Dilution: Western Blotting1:1000-1:5000 for neat serum and 1-10ug/ml for affinity pure antibody using ECL technique. ELISA:1:10,000-50,000 for neat serum and 0.5-1ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1ug/ml. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Slc21a4 slco1a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Organic Anion Transporter K1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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