Rabbit anti-Mouse GFR alpha3 Polyclonal Antibody
GFR alpha3 (Glycosylphosphadidylinositol linked Protein, GDNFRg, Ret ligand 3, RETL3)
Reactivity
Mouse
Applications
Western Blot
Purity
PurifiedPurified
Synonyms
GFR alpha3; Polyclonal Antibody; GFR alpha3 (Glycosylphosphadidylinositol linked Protein; GDNFRg; Ret ligand 3; RETL3); Anti -GFR alpha3 (Glycosylphosphadidylinositol linked Protein; anti-GFR alpha3 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
GFRa-3 binds persephin; persephin, GFRa-3 and the Ret PTK form a complex to transduce persephin signal and to mediate persephin function.
Purity/Purification
Purified
Purified
Purified
Form/Format
Purified IgG in PBS containing 0.02% sodium azide.
Applicable Applications for anti-GFR alpha3 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:500-1:1000
Mouse kidney, liver or heart tissue lysates can be used as positive controls
Mouse kidney, liver or heart tissue lysates can be used as positive controls
Immunogen
Peptide corresponding to the amino acids 347-360 of mouse GFRa-3.
Preparation and Storage
-20 degree C
Related Product Information for anti-GFR alpha3 antibody
Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin (1). Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRa and Ret receptor tyrosine kinase GFRb (2). Following the findings of GFRa-1 and-2, a novel receptor in GFRa family was identified very recently from human and mouse and designated GFRa-3 (3-7)
Product Categories/Family for anti-GFR alpha3 antibody
Similar Products
Product Notes
The GFR alpha3 (Catalog #AAA615976) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GFR alpha3 (Glycosylphosphadidylinositol linked Protein, GDNFRg, Ret ligand 3, RETL3) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GFR alpha3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:1000 Mouse kidney, liver or heart tissue lysates can be used as positive controls. Researchers should empirically determine the suitability of the GFR alpha3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GFR alpha3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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