Mouse anti-Human CTDP1 Monoclonal Antibody | anti-CTDP1 antibody

CTDP1 (RNA Polymerase II Subunit A C-terminal Domain Phosphatase, TFIIF-associating CTD Phosphatase, FCP1) (FITC)

Cat. Num. AAA6146698

• Gene Names: CTDP1; FCP1; CCFDN
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CTDP1; Monoclonal Antibody; CTDP1 (RNA Polymerase II Subunit A C-terminal Domain Phosphatase; TFIIF-associating CTD Phosphatase; FCP1) (FITC); anti-CTDP1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 3G4
• Specificity: Recognizes human CTDP1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
• Sequence Length: 3569

• Applicable Applications for anti-CTDP1 antibody: ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IHC-P: 3ug/ml; Applications are based on unconjugated antibody.
• Immunogen: Partial recombinant corresponding to aa332-432 from CTDP1 (AAH63447) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: PPGSRESQTRKKVNHSRGTEVSEPSPPVRDPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQELAGAPEPQGSCAQ
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (37.11kD).)

Western Blot (WB)

(CTDP1 monoclonal antibody Western Blot analysis of CTDP1 expression in HepG2)

Immunohistochemistry (IHC)

(Immunoperoxidase of monoclonal antibody to CTDP1 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3ug/ml])

Testing Data

(Detection limit for recombinant GST tagged CTDP1 is ~0.03ng/ml as a capture antibody.)

Product Categories/Family for anti-CTDP1 antibody

Antibodies; Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 39645773
• NCBI GeneID: 9150
• NCBI Official Full Name: Homo sapiens CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1, mRNA
• NCBI Official Synonym Full Names: CTD phosphatase subunit 1
• NCBI Official Symbol: CTDP1
• NCBI Official Synonym Symbols: FCP1; CCFDN
• NCBI Protein Information: RNA polymerase II subunit A C-terminal domain phosphatase

NCBI Description

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]