Mouse anti-Human SCYE1 Monoclonal Antibody | anti-SCYE1 antibody

SCYE1 (Aminoacyl tRNA Synthase Complex-interacting Multifunctional Protein 1, AIMP1, EMAP2, EMAPII, HLD3, Multisynthase Complex Auxiliary Component p43, p43) (Biotin)

Cat. Num. AAA6144247

• Gene Names: AIMP1; p43; HLD3; EMAP2; SCYE1; EMAPII
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SCYE1; Monoclonal Antibody; SCYE1 (Aminoacyl tRNA Synthase Complex-interacting Multifunctional Protein 1; AIMP1; EMAP2; EMAPII; HLD3; Multisynthase Complex Auxiliary Component p43; p43) (Biotin); anti-SCYE1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 3H5
• Specificity: Recognizes human SCYE1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 1758

• Applicable Applications for anti-SCYE1 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-312 from human SCYE1 (AAH14051) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (60.06kD).)

Western Blot (WB)

(SCYE1 monoclonal antibody Western Blot analysis of SCYE1 expression in Jurkat)

Testing Data

(Detection limit for recombinant GST tagged SCYE1 is ~3ng/ml as a capture antibody.)

Product Categories/Family for anti-SCYE1 antibody

Antibodies; Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 33878437
• NCBI GeneID: 9255
• NCBI Official Full Name: Homo sapiens small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating), mRNA
• NCBI Official Synonym Full Names: aminoacyl tRNA synthetase complex interacting multifunctional protein 1
• NCBI Official Symbol: AIMP1
• NCBI Official Synonym Symbols: p43; HLD3; EMAP2; SCYE1; EMAPII
• NCBI Protein Information: aminoacyl tRNA synthase complex-interacting multifunctional protein 1

NCBI Description

The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]