Western Blot (WB)
(Western Blot detection against Immunogen (64.61kD))
Mouse anti-Human PARVB Monoclonal Antibody | anti-PARVB antibody
PARVB (Beta-parvin, Affixin, CGI-56) APC
Gene Names
PARVB; CGI-56
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PARVB; Monoclonal Antibody; PARVB (Beta-parvin; Affixin; CGI-56) APC; anti-PARVB antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
4A11
Specificity
Recognizes human PARVB.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-PARVB antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length recombinant corresponding to aa1-351 from human PARVB (AAH46103) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MKKDESFLGKLGGTLARKRRAREVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLN
Conjugate
APC
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen (64.61kD))
Western Blot (WB)
(Western Blot detection against Immunogen (64.61kD))
Western Blot (WB)
(Western Blot analysis of PARVB expression in transfected 293T cell line by PARVB monoclonal antibody. Lane 1: PARVB transfected lysate (40.25kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PARVB expression in transfected 293T cell line by PARVB monoclonal antibody. Lane 1: PARVB transfected lysate (40.25kD). Lane 2: Non-transfected lysate.)
Testing Data
(Detection limit for recombinant GST tagged PARVB is 1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged PARVB is 1ng/ml as a capture antibody.)
Related Product Information for anti-PARVB antibody
Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.
Product Categories/Family for anti-PARVB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
37,538 Da
NCBI Official Full Name
Homo sapiens parvin, beta, mRNA
NCBI Official Synonym Full Names
parvin beta
NCBI Official Symbol
PARVB
NCBI Official Synonym Symbols
CGI-56
NCBI Protein Information
beta-parvin
Protein Family
NCBI Description
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Research Articles on PARVB
Similar Products
Product Notes
The PARVB (Catalog #AAA6138073) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PARVB (Beta-parvin, Affixin, CGI-56) APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PARVB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PARVB for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARVB, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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