anti-Rat Prostaglandin Transporter Polyclonal Antibody | anti-SLCO2A1 antibody
Anti - Prostaglandin Transporter (PGT)
Gene Names
SLCO2A1; PGT; MATR1; OATP2A1; SLC21A2
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
Prostaglandin Transporter; Polyclonal Antibody; Anti - Prostaglandin Transporter (PGT); Prostaglandin Transporter (PGT); anti-SLCO2A1 antibody
Host
Host: Rabbit
Source: Rat
Source: Rat
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat PGT. No significant sequence homology is detected with other oatp1-3, OATP or LST-1.
Purity/Purification
Serum
Form/Format
Serum
Supplied as a liquid, neat serum, 40% glycerol.
Supplied as a liquid, neat serum, 40% glycerol.
Sequence Length
643
Applicable Applications for anti-SLCO2A1 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA and Western Blot. Other applications not tested.
Dilution: Western Blot: 1:1000-1:5000 for neat serum and 1-10ug/ml for affinity pure using ECL. A band of 95-110kD has been detected in brush border membrane (2).
ELISA:1:10,000-50,000 for neat serum and 0.5-1ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Dilution: Western Blot: 1:1000-1:5000 for neat serum and 1-10ug/ml for affinity pure using ECL. A band of 95-110kD has been detected in brush border membrane (2).
ELISA:1:10,000-50,000 for neat serum and 0.5-1ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Immunogen
20aa peptide from the C-terminus region of Rat PGT (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-SLCO2A1 antibody
Mammalian kidney and liver are critical in maintaining physiological ionic environment. Kidney specializes in removing toxins, drugs, and other organic anions from the blood by a process called "renal secretion". Besides kidney, anionic substrates are also transported in other organs, e.g., choroid plexus, eye, airway, and placenta. Several multispecific OATs (OAT1-3, OAT-K1 and OATK2) and OATPs (organic anion transporting polypeptides; oatp1-3, LST-1, and PGT), have been cloned and characterized from various tissues. OATPs family of proteins share significant sequence homology, and general secondary protein structure (up to 12 transmembrane domains with cytoplasmic N and C-terminus). Prostaglandins and thromboxanes play important physiological, pathological, and therapeutical roles in health and disease. PGT prostaglandin transporter also known as martin F/G), a member of oatp family, mediates transport of PGs (PGD2, PGE1, PGE2, PGF2a) from the circulation. PGT (rat/human 643 aa; 12 TM) is
Product Categories/Family for anti-SLCO2A1 antibody
References
• Kanai N et al (19950 Science 268, 866-869; Lu R et al (1996) J Clin. Invest. 98, 1142-1149 Kis B 2006 J Appl Physiol 100, 1392-1399 Scafidi S 2007 Neuroscience, 146, (2007) 1150-1157.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
70,044 Da
NCBI Official Full Name
prostaglandin transporter
NCBI Official Synonym Full Names
solute carrier organic anion transporter family, member 2A1
NCBI Official Symbol
SLCO2A1
NCBI Official Synonym Symbols
PGT; MATR1; OATP2A1; SLC21A2
NCBI Protein Information
solute carrier organic anion transporter family member 2A1; matrin F/G 1; OTTHUMP00000216361; OTTHUMP00000216362; OTTHUMP00000216363; prostaglandin transporter; solute carrier family 21 member 2; solute carrier family 21 (prostaglandin transporter), member 2
UniProt Protein Name
Solute carrier organic anion transporter family member 2A1
Protein Family
UniProt Gene Name
SLCO2A1
UniProt Synonym Gene Names
OATP2A1; SLC21A2
UniProt Entry Name
SO2A1_HUMAN
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Product Notes
The SLCO2A1 slco2a1 (Catalog #AAA611028) is an Antibody produced from Host: Rabbit Source: Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti - Prostaglandin Transporter (PGT) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Prostaglandin Transporter can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA and Western Blot. Other applications not tested. Dilution: Western Blot: 1:1000-1:5000 for neat serum and 1-10ug/ml for affinity pure using ECL. A band of 95-110kD has been detected in brush border membrane (2). ELISA:1:10,000-50,000 for neat serum and 0.5-1ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1ug/ml. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the SLCO2A1 slco2a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prostaglandin Transporter, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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