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Rabbit anti-Mouse Metal Transporter Protein Polyclonal Antibody

Metal Transporter Protein (MTP1)

Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Serum
Serum
Synonyms
Metal Transporter Protein; Polyclonal Antibody; Metal Transporter Protein (MTP1); Anti -Metal Transporter Protein (MTP1); anti-Metal Transporter Protein antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse Metal Transporter Protein. Does not distinguish between isoforms ferroprotein1/IREG1, ferroprotein 1 and IRG1/ferroprotein1.
Purity/Purification
Serum
Serum
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Applicable Applications for anti-Metal Transporter Protein antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000 (ECL)
ELISA: 1:10,000-1: 50,000. Coat with 1ug/ml Control Peptide.
Immunogen
Synthetic peptide corresponding to19aa within the predicted cytoplasmic C-terminus of mouse MTP1 (KLH).Species Sequence Homology: mouse ferroprotein1/IREG1,100%; rat ferroprotein 1, 90%; human, chimp IREG1/ferroprotein1, 78%; rabbit MTP1/REG1/ ferroprotein1, 73%.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Related Product Information for anti-Metal Transporter Protein antibody
A novel iron-regulated gene that is homologous to the DMAT1, termed Metal Transporter Protein (MTP1, human 571aa, mouse 570aa; ~90% similarity), has been identified. MTP1 is also described as iron-regulated transporter (IREG1), Ferroportin1 and SLC11A3 iron transporter or solute carrier family 11 (proton coupled divalent metal ion transporter), Member 3, formerly SLC11A3). MTP1 contains IRE in the 5'-UTR. It is expressed in tissues involved in body iron homeostasis including the developing and mature reticuloendothelial system, the duodenum and the pregnant uterus. MTP1 is also expressed in muscle and central nervous system cells in the embryo. In the adult mouse, MTP1 expression in the liver and duodenum are reciprocally regulated. Iron deficiency induces MTP1 expression in the duodenum but down-regulates expression in the liver. Therefore, MTP1 appears to be an iron-regulated protein that is involved in iron metabolism.
Product Categories/Family for anti-Metal Transporter Protein antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
metal transporter protein

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Product Notes

The Metal Transporter Protein (Catalog #AAA610361) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Metal Transporter Protein (MTP1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Metal Transporter Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000-1:5000 (ECL) ELISA: 1:10,000-1: 50,000. Coat with 1ug/ml Control Peptide. Researchers should empirically determine the suitability of the Metal Transporter Protein for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Metal Transporter Protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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