Mouse anti-Human IARS Monoclonal Antibody | anti-IARS antibody
IARS (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, Isoleucine-tRNA Ligase)
Purified.
Purified.
NCBI and Uniprot Product Information
NCBI Description
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
Uniprot Description
IARS: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs. [provided by RefSeq, Jul 2008]
Protein type: Ligase; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 6.1.1.5; Translation
Chromosomal Location of Human Ortholog: 9q21
Cellular Component: nucleoplasm; membrane; cytoplasm; cytosol
Molecular Function: protein binding; ATP binding; isoleucine-tRNA ligase activity
Biological Process: osteoblast differentiation; isoleucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expression
Research Articles on IARS
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Product Notes
The IARS iars (Catalog #AAA609527) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IARS (Isoleucyl-tRNA Synthetase Cytoplasmic, IARS1, IleRS, ILRS, IRS, Isoleucine-tRNA Ligase) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IARS can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the IARS iars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IARS, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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