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Mouse anti-Human DDX6 Monoclonal Antibody | anti-DDX6 antibody

DDX6 (DDX-6, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6, DEAD Box Protein 6, FLJ36338, HLR2, HLR-2, P54 RNA Helicase, RCK) (Azide Free)

Gene Names
DDX6; P54; RCK; HLR2; FLJ36338
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified
Purified by ammonium sulfate precipitation.
Synonyms
DDX6; Monoclonal Antibody; DDX6 (DDX-6; DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6; DEAD Box Protein 6; FLJ36338; HLR2; HLR-2; P54 RNA Helicase; RCK) (Azide Free); Anti -DDX6 (DDX-6; anti-DDX6 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
10B2681
Specificity
Recognizes human DDX6 at ~54kD.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added.
Applicable Applications for anti-DDX6 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry: 1.5ug/ml
ELISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1000
Immunogen
Recombinant protein corresponding to aa1-484 of human DDX6 with a GST tag (26kD).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-DDX6 antibody
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.
Product Categories/Family for anti-DDX6 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
54,417 Da
NCBI Official Full Name
DDX6 protein
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
NCBI Official Symbol
DDX6
NCBI Official Synonym Symbols
P54; RCK; HLR2; FLJ36338
NCBI Protein Information
probable ATP-dependent RNA helicase DDX6; DEAD box-6; oncogene RCK; DEAD box protein 6; OTTHUMP00000232837; OTTHUMP00000232838; ATP-dependent RNA helicase p54; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD)
UniProt Protein Name
Probable ATP-dependent RNA helicase DDX6
UniProt Gene Name
DDX6
UniProt Synonym Gene Names
HLR2; RCK
UniProt Entry Name
DDX6_HUMAN

NCBI Description

This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. [provided by RefSeq]

Uniprot Description

DDX6: an oncogenic ATP-dependent helicase of the DEAD box family. Interacts with argonaute proteins, Ago1 and Ago2, and is a general repressor of translation in human cells by miRNA-induced gene silencing. In the process of mRNA degradation, may play a role in mRNA decapping.

Protein type: RNA-binding; EC 3.6.4.13; Oncoprotein; RNA processing; Helicase

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: membrane; intracellular membrane-bound organelle; stress granule; cytoplasm; cytosol

Molecular Function: protein domain specific binding; protein binding; helicase activity; RNA helicase activity; ATP binding

Biological Process: cytoplasmic mRNA processing body assembly; gene expression; mRNA catabolic process, deadenylation-dependent decay

Research Articles on DDX6

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Product Notes

The DDX6 ddx6 (Catalog #AAA607071) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DDX6 (DDX-6, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6, DEAD Box Protein 6, FLJ36338, HLR2, HLR-2, P54 RNA Helicase, RCK) (Azide Free) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DDX6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Immunohistochemistry and Western Blot. Dilution: Immunohistochemistry: 1.5ug/ml ELISA: 1ug/ml-3ng/ml Western Blot: 1:500-1:1000. Researchers should empirically determine the suitability of the DDX6 ddx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDX6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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