Mouse anti-Mouse MHC Class 1, H-2Kb Monoclonal Antibody | anti-H2-D1 antibody

MHC Class 1, H-2Kb (MHC Class I H-2Kb, H-2 Class I Histocompatibility Antigen K-B alpha Chain, H-2K(B), H2-K1, H-2K, H2-K, H-2K(d), MGC7052, MGC184092)

Cat. Num. AAA604512

• Gene Names: H2-D1; H-2D; H2-D
• Reactivity: Mouse
• Applications: Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: MHC Class 1; H-2Kb; Monoclonal Antibody; H-2Kb (MHC Class I H-2Kb; H-2 Class I Histocompatibility Antigen K-B alpha Chain; H-2K(B); H2-K1; H-2K; H2-K; H-2K(d); MGC7052; MGC184092); Anti -MHC Class 1; anti-H2-D1 antibody

• Host: Mouse
• Reactivity: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone Number: AF6-88.5
• Specificity: Recognizes the mouse MHC Class I H-2Kb antigen. Does not cross react with other haplotypes.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-H2-D1 antibody: Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation.; Dilution: Flow Cytometry: 1:10-1:20. Use 10ul to label 10e6 cells in 100ul.; Immunohistochemistry: Frozen; Optimal working dilutions to be determined by researcher.
• Immunogen: Mouse MHC Class 1, H2, Kb
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-H2-D1 antibody

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region. There are 3 major MHC class I proteins encoded by the H-2 which are H-2K, H-2L and H-2D. The H- 2K gene is part of the murine H-2 complex on chromosome 17 and there are a large number of variant alleles of this gene.

Product Categories/Family for anti-H2-D1 antibody

Antibodies; Abs to MHC

NCBI and Uniprot Product Information

• NCBI GI #: 554241
• NCBI GeneID: 14964
• UniProt Accession #: O19453; Q9QUL2; O19467; O19473; O19476; O78206; O78207; P01895; P01896; P01897; P01899
• Molecular Weight: 16,970 Da
• NCBI Official Full Name: MHC class I H2 antigen
• NCBI Official Synonym Full Names: histocompatibility 2, D region locus 1
• NCBI Official Symbol: H2-D1
• NCBI Official Synonym Symbols: H-2D; H2-D
• NCBI Protein Information: H-2 class I histocompatibility antigen, L-D alpha chain; Q5k protein; MHC class I H-2Dp; MHC H2-D-q alpha-chain; MHC class I H2 antigen; H-2D cell surface glycoprotein; H2-DC1-beta transplantation antigen protein
• UniProt Protein Name: Cell surface glycoprotein
• Protein Family: H-2 class I histocompatibility antigen
• UniProt Gene Name: H2-D1
• UniProt Synonym Gene Names: H-2L(q)
• UniProt Entry Name: O19453_MOUSE

Uniprot Description

KLC2: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Belongs to the kinesin light chain family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; Motor

Cellular Component: ciliary rootlet; microtubule; kinesin complex; neuron projection; cytoskeleton; protein complex; membrane; cell; cytoplasm; intracellular; cytosol

Molecular Function: protein binding; kinesin binding; microtubule motor activity

Biological Process: axon cargo transport; microtubule-based movement