Mouse HIV-1 gag p55 Monoclonal Antibody
HIV-1 gag p55 (Human Immunodeficiency Virus-1)
Applications
ELISA, Western Blot
Purity
Purified by Protein G affinity chromatography.
Synonyms
HIV-1 gag p55; Monoclonal Antibody; HIV-1 gag p55 (Human Immunodeficiency Virus-1); Anti -HIV-1 gag p55 (Human Immunodeficiency Virus-1); anti-HIV-1 gag p55 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5i78
Specificity
Recognizes the C-terminal region from aa370-501 of gag p55. Since it does not recognize the p17 and p24 sequences, it can be used to differentiate the p17 and p24 regions of the gag polyprotein.
Purity/Purification
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Concentration
1mg/m (varies by lot)
Applicable Applications for anti-HIV-1 gag p55 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:30,000
Western Blot: 1:8000
Optimal dilutions to be determined by the researcher.
Other applications not tested.
Western Blot: 1:8000
Optimal dilutions to be determined by the researcher.
Other applications not tested.
Type
Mab
Grade
Affinity Purified
Immunogen
HIV-1 gag polyprotein (55kD).
Preparation and Storage
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-HIV-1 gag p55 antibody
Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells), macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosisin infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunityis lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genomeis converted to double-stranded DNAby a virally encoded reverse transcriptasethat is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integraseso that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latentand the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells.
Product Categories/Family for anti-HIV-1 gag p55 antibody
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Product Notes
The HIV-1 gag p55 (Catalog #AAA602727) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HIV-1 gag p55 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:30,000 Western Blot: 1:8000 Optimal dilutions to be determined by the researcher. Other applications not tested. Researchers should empirically determine the suitability of the HIV-1 gag p55 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HIV-1 gag p55, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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