Rabbit anti-Human, Mouse SYT7 Polyclonal Antibody | anti-SYT7 antibody

SYT7, NT (SYT7, PCANAP7, Synaptotagmin-7, IPCA-7, Prostate cancer-associated protein 7, Synaptotagmin VII)

Cat. Num. AAA6011756

• Gene Names: SYT7; IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SYT7; Polyclonal Antibody; NT (SYT7; PCANAP7; Synaptotagmin-7; IPCA-7; Prostate cancer-associated protein 7; Synaptotagmin VII); Anti -SYT7; anti-SYT7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-SYT7 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: SYT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-101 amino acids from the N-terminal region of human SYT7.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SYT7 Antibody (N-term) western blot analysis in human uterine tomer tissue lysates (35ug/lane).This demonstrates the SYT7 antibody detected the SYT7 protein (arrow).)

Western Blot (WB)

(SYT7 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SYT7 antibody detected the SYT7 protein (arrow).)

Related Product Information for anti-SYT7 antibody

Synaptotagmins, such as SYT7, are brain-specific calcium-dependent phospholipid-binding proteins that play a role in synaptic exocytosis and neurotransmitter release. See MIM 600782.

Product Categories/Family for anti-SYT7 antibody

Antibodies; Abs to Cancer Markers

NCBI and Uniprot Product Information

• NCBI GI #: 354983504
• NCBI GeneID: 9066
• NCBI Accession #: NP_001238994.1
• NCBI GenBank Nucleotide #: NM_001252065.1
• UniProt Accession #: O43581; Q08AH6; F5GZU9
• Molecular Weight: 45,501 Da
• NCBI Official Full Name: synaptotagmin-7 isoform 1
• NCBI Official Synonym Full Names: synaptotagmin VII
• NCBI Official Symbol: SYT7
• NCBI Official Synonym Symbols: IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII
• NCBI Protein Information: synaptotagmin-7; prostate cancer-associated protein 7
• UniProt Protein Name: Synaptotagmin-7
• Protein Family: Synaptotagmin
• UniProt Gene Name: SYT7
• UniProt Synonym Gene Names: PCANAP7; SytVII
• UniProt Entry Name: SYT7_HUMAN

NCBI Description

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

SYT7: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: synaptic vesicle membrane; lysosome; integral to membrane; plasma membrane; cell junction

Molecular Function: calcium-dependent phospholipid binding; transporter activity; calcium ion binding

Biological Process: positive regulation of calcium ion-dependent exocytosis; exocytosis; plasma membrane repair; regulation of insulin secretion