Rabbit anti-Human GJC3 Polyclonal Antibody | anti-GJC3 antibody

GJC3, CT (GJC3, GJE1, Gap junction gamma-3 protein, Connexin-30.2, Connexin-31.3, Gap junction epsilon-1 protein)

Cat. Num. AAA6010637

• Gene Names: GJC3; CX29; GJE1; CX30.2; CX31.3
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: GJC3; Polyclonal Antibody; CT (GJC3; GJE1; Gap junction gamma-3 protein; Connexin-30.2; Connexin-31.3; Gap junction epsilon-1 protein); Anti -GJC3; anti-GJC3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-GJC3 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: GJC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of human GJC3.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(GJC3 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GJC3 antibody detected the GJC3 protein (arrow).)

Related Product Information for anti-GJC3 antibody

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.

Product Categories/Family for anti-GJC3 antibody

Antibodies; Abs to Connexin; Junction Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 31559821
• NCBI GeneID: 349149
• NCBI Accession #: NP_853516.1
• NCBI GenBank Nucleotide #: NM_181538.2
• UniProt Accession #: Q8NFK1; Q86XI9; A4D296
• Molecular Weight: 31,299 Da
• NCBI Official Full Name: gap junction gamma-3 protein
• NCBI Official Synonym Full Names: gap junction protein, gamma 3, 30.2kDa
• NCBI Official Symbol: GJC3
• NCBI Official Synonym Symbols: CX29; GJE1; CX30.2; CX31.3
• NCBI Protein Information: gap junction gamma-3 protein; connexin 29; connexin-30.2; connexin-31.3; gap junction epsilon-1 protein
• UniProt Protein Name: Gap junction gamma-3 protein
• Protein Family: Gap junction gamma-3 protein
• UniProt Gene Name: GJC3
• UniProt Synonym Gene Names: GJE1; Cx30.2; Cx31.3
• UniProt Entry Name: CXG3_HUMAN

NCBI Description

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010]

Uniprot Description

GJC3: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: connexon complex; integral to membrane; myelin sheath

Molecular Function: protein homodimerization activity

Biological Process: myelination; sensory perception of sound; cell communication