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Immunohistochemistry (IHC) (Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with AFF1 antibody at 10ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Rabbit anti-Human MLLT2 Polyclonal Antibody

MLLT2 (AF4/FMR2 Family Member 1, ALL1-fused Gene From Chromosome 4 Protein, Protein AF-4, Proto-oncogene AF4, Protein FEL, AFF1, AF4, FEL, PBM1)

Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Purified
Purified.
Synonyms
MLLT2; Polyclonal Antibody; MLLT2 (AF4/FMR2 Family Member 1; ALL1-fused Gene From Chromosome 4 Protein; Protein AF-4; Proto-oncogene AF4; Protein FEL; AFF1; AF4; FEL; PBM1); Anti -MLLT2 (AF4/FMR2 Family Member 1; anti-MLLT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human MLLT2.
Purity/Purification
Purified
Purified.
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide.
Applicable Applications for anti-MLLT2 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Immunogen
Synthetic peptide corresponding to aa1190-1203 of human MLLT2 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with AFF1 antibody at 10ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Immunohistochemistry (IHC) (Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with AFF1 antibody at 10ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Immunohistochemistry (IHC)

(Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with AFF1 antibody at 10ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Immunohistochemistry (IHC) (Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with AFF1 antibody at 10ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Related Product Information for anti-MLLT2 antibody
MLLT2 is involved in acute leukemias through a chromosomal translocation t(4;11)(q21;q23) that involves mllt2 and mll/hrx. AF-4 (MLLT2), AF-9, and ENL proteins contain nuclear targeting sequences as well as serine-rich and proline-rich regions. Stretches abundant in basic aa are also present in the three proteins. These results suggest that the different proteins fused to ALL-1 polypeptide(s) provide similar functional domains. AF4 is a serine- and proline-rich putative transcription factor with a glutamine-rich carboxyl terminus. The composition of the complete MLL-AF4 fusion product argues that it may act through either a gain-of-function or a dominant negative mechanism in leukemogenesis.
Product Categories/Family for anti-MLLT2 antibody

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Product Notes

The MLLT2 (Catalog #AAA6010387) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MLLT2 (AF4/FMR2 Family Member 1, ALL1-fused Gene From Chromosome 4 Protein, Protein AF-4, Proto-oncogene AF4, Protein FEL, AFF1, AF4, FEL, PBM1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MLLT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry. Dilution: ELISA: 1:1000 Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml. Researchers should empirically determine the suitability of the MLLT2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLLT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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