Goat LPIN2 Polyclonal Antibody | anti-Lpin2 antibody
LPIN2 (Lipin 2, Phosphatidate Phosphatase LPIN2, Lipin-2, KIAA0249)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: ELISA: 1:8000
NCBI and Uniprot Product Information
Uniprot Description
LPIN2: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism. Defects in LPIN2 are the cause of Majeed syndrome (MAJEEDS). An autosomal recessive syndrome characterized by chronic recurrent multifocal osteomyelitis that is of early onset with a lifelong course, congenital dyserythropoietic anemia that presents as hypochromic, microcytic anemia during the first year of life and ranges from mild to transfusion-dependent, and transient inflammatory dermatosis, often manifesting as Sweet syndrome (neutrophilic skin infiltration). Belongs to the lipin family.
Protein type: EC 3.1.3.4; Transcription, coactivator/corepressor; Phosphatase (non-protein)
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytoplasm; nucleus; cytosol
Molecular Function: hydrolase activity; phosphatidate phosphatase activity; transcription coactivator activity
Biological Process: transcription, DNA-dependent; dephosphorylation; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; triacylglycerol biosynthetic process; fatty acid catabolic process; lipid metabolic process; fatty acid metabolic process
Research Articles on Lpin2
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Product Notes
The Lpin2 lpin2 (Catalog #AAA6008276) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The LPIN2 (Lipin 2, Phosphatidate Phosphatase LPIN2, Lipin-2, KIAA0249) reacts with Human, Mouse, Porcine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LPIN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: ELISA: 1:8000. Researchers should empirically determine the suitability of the Lpin2 lpin2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LPIN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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